RSS 1.0Departamento de Física
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Diffusion of tRNA inside the ribosome is position-dependent
; ; ; Leite, Vitor B. P.
; Chahine, Jorge ; (Journal of Chemical Physics, 2019) [Artigo]
In recent years, there has been a growing interest to quantify the energy landscape that governs ribosome dynamics. However, in order to quantitatively integrate theoretical predictions and experimental measurements, it ... -
Brown spider (Loxosceles) venom toxins as potential biotools for the development of novel therapeutics
(Toxins, 2019) [Resenha]Brown spider envenomation results in dermonecrosis with gravitational spreading characterized by a marked inflammatory reaction and with lower prevalence of systemic manifestations such as renal failure and hematological ... -
A panel of recombinant proteins for the serodiagnosis of caseous lymphadenitis in goats and sheep
; Mariutti, Ricardo Barros; Arni, Raghuvir Krishnaswamy ; ; ; ; ; ; ; (Microbial Biotechnology, 2019) [Artigo]
Caseous lymphadenitis (CLA) is a small ruminant disease characterized by the development of granulomatous lesions in superficial and internal lymph nodes, as well as in some organs, and causes significant economic losses ... -
On the charge transport mechanism of cross-linked PEDOT:PSS films
Colucci, Renan; ; Santos, Lucas Fugikawa ; Gozzi, Giovani (Journal of Materials Science: Materials in Electronics, 2019) [Artigo]
Conductive composites based on cross-linked poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) blends have been widely applied to produce electronic devices, such as organic electrochemical transistor, ... -
Analytic results of the DNA thermal denaturation in the Peyrard-Bishop-Dauxois model
Drigo Filho, E.; ; Ribeiro, N. F. (Journal of Physics: Conference Series, 2019) [Trabalho apresentado em evento]
The thermal denaturation of the DNA within the Peyrard-Bishop-Dauxois (PBD) model is analyzed analytically through the variational method adapted to determine the ground state energy of a Schrödinger-like equation with ... -
Vibrational ground state energy for confined molecules
Filho, Elso Drigo; Silva, Josimar Fernando Da (Journal of Physics: Conference Series, 2019) [Trabalho apresentado em evento]
The ground state vibrational energies for three confined diatomic molecules (nitrogen, lithium and NaH) are determined by using the variational method. The approach proposed allows us to build trial eigenfunctions based ... -
On the UV-light-induced Desorption/Adsorption Mechanism of Atmospheric Species in Solution-processed Zinc Oxide Thin Films
Cantuária, José Bruno; Gozzi, Giovani ; Santos, Lucas Fugikawa (MRS Advances, 2019) [Trabalho apresentado em evento]
Zinc oxide (ZnO) is a n-type transparent semiconductor which can be processed by low cost techniques (such as spray-pyrolysis and spin-coating) and can be applied as the active layer of thin-films transistors (TFTs). The ... -
Experimental approaches and computational modeling of rat serum albumin and its interaction with piperine
Zazeri, Gabriel; Povinelli, Ana Paula Ribeiro ; Lima, Marcelo De Freitas ; Cornélio, Marinônio Lopes (International Journal of Molecular Sciences, 2019) [Artigo]
The bioactive piperine (1-piperoyl piperidine) compound found in some pepper species (Piper nigrum linn and Piper sarmentosum Roxb) has been shown to have therapeutic properties and to be useful for well-being. The tests ... -
Synthesis and Characterization of Peptide-Chitosan Conjugates (PepChis) with Lipid Bilayer Affinity and Antibacterial Activity
; Fadel, Valmir; Martins, Danubia B. ; ; ; ; ; ; Dos Santos Cabrera, Marcia P. (Biomacromolecules, 2019) [Artigo]
Antimicrobial peptides appear among innovative biopolymers with potential therapeutic interest. Nevertheless, issues concerning efficiency, production costs, and toxicity persist. Herein, we show that conjugation of peptides ... -
Prediction of the electrical response of solution-processed thin-film transistors using multifactorial analysis
Braga, João P.; Moises, Lucas A. ; Gozzi, Giovani ; Fugikawa-Santos, Lucas (Journal of Materials Science: Materials in Electronics, 2019) [Artigo]
Thin-film transistors (TFTs) with the active layer composed by zinc oxide (ZnO) deposited via spray-pyrolysis present several advantages such as high electrical performance, high optical transmittance in the visible spectrum, ... -
An investigation into the interaction between piplartine (piperlongumine)and human serum albumin
de Alcântara-Contessoto, Nayara Sousa; Caruso, Ícaro Putinhon ; ; ; Cornélio, Marinônio Lopes (Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2019) [Artigo]
Piplartines are alkaloid amides present in the roots and stems of different pepper species which have promising pharmacological properties including cancer prevention. Some recent studies have determined pharmacokinetic ... -
Binding studies of a putative C. pseudotuberculosis target protein from Vitamin B 12 Metabolism
Peinado, Rafaela Dos S; Olivier, Danilo S. ; Eberle, Raphael J. ; de Moraes, Fabio R. ; ; Arni, Raghuvir K. ; Coronado, Monika A. (Scientific reports, 2019) [Artigo]
Vitamin B12 acts as a cofactor for various metabolic reactions important in living organisms. The Vitamin B12 biosynthesis is restricted to prokaryotes, which means, all eukaryotic organisms must acquire this molecule ... -
Behavior of Sweet Potato Starch After Spray-Drying Under Different Pretreatment Conditions
dos Santos, Thais Paes Rodrigues; Franco, Célia Maria Landi ; Mischan, Martha Maria ; Leonel, Magali (Starch/Staerke, 2019) [Artigo]
There are a lot of potential uses of sweet potato as a source of starch in food and other industries. Pregelatinization, a physical modification that confers properties of interest for several industrial applications, is ... -
Biophysical and flavonoid-binding studies of the G protein ectodomain of group A human respiratory syncytial virus
Machado, Vitor Brassolatti; Maróstica de Sá, Jéssica ; Miranda Prado, Ana Karla ; Alves de Toledo, Karina ; Regasini, Luis Octávio ; Pereira de Souza, Fátima ; Caruso, Ícaro Putinhon ; Fossey, Marcelo Andres (Heliyon, 2019) [Artigo]
The human Respiratory Syncytial Virus (hRSV) is the major causative agent of lower respiratory tract diseases in infants, young children and elderly. The membrane protein G is embedded in the viral lipid envelope and plays ... -
The polyanions heparin and suramin impede binding of free adenine to a DNA glycosylase from C. pseudotuberculosis
Eberle, Raphael J.; Coronado, Monika A. ; Peinado, Rafaela S. ; de Moraes, Fabio R. ; Olivier, Danilo ; Dreyer, Thiago ; ; ; ; Arni, Raghuvir K. (International Journal of Biological Macromolecules, 2019) [Artigo]
Currently no effective treatment is available to combat infections caused by Corynebacterium pseudotuberculosis in livestock. Survival of this Gram-positive bacterium in rapidly-growing pathogens in hostile environments ... -
Zika virus NS2B/NS3 proteinase: A new target for an old drug - Suramin a lead compound for NS2B/NS3 proteinase inhibition-
Coronado, Monika Aparecida; Eberle, Raphael Josef ; ; ; Olivier, Danilo Silva ; de Moraes, Fabio Rogerio ; ; Arni, Raghuvir Krishnaswamy (Antiviral Research, 2018) [Artigo]
Zika virus infection is the focus of much research due to the medical and social repercussions. Due the role of the viral NS2B/NS3 proteinase in maturation of the viral proteins, it had become an attractive antiviral target. ... -
Effects of temperature and pectin edible coatings with guava by-products on the drying kinetics and quality of dried red guava
Todisco, Katieli Martins; Janzantti, Natália Soares ; Santos, Adriana Barbosa ; Galli, Felipe Sestari ; Mauro, Maria Aparecida (Journal of Food Science and Technology, 2018) [Artigo]
With the objective of utilizing agro-industrial by-products and enhancing the quality attributes of dehydrated fruits, this study evaluated the effects of edible pectin-based coatings containing disintegrated guava by-products ... -
Structural analysis of a novel N-carbamoyl-D-amino acid amidohydrolase from a Brazilian Bradyrhizobium japonicum strain: In silico insights by molecular modelling, docking and molecular dynamics
; Coronado, Mônika Aparecida; ; ; ; ; (Journal of Molecular Graphics and Modelling, 2019) [Artigo]
In this work we performed several in silico analyses to describe the relevant structural aspects of an enzyme N-Carbamoyl-D-amino acid amidohydrolase (D-NCAase) encoded on the genome of the Brazilian strain CPAC 15 (=SEMIA ... -
The effect of pH on the lytic activity of a synthetic mastoparan-like peptide in anionic model membranes
Alvares, Dayane S.; Viegas, Taisa G. ; Ruggiero Neto, João (Chemistry and Physics of Lipids, 2018) [Artigo]
Peptide sequences containing acidic and basic residues could potentially have their net charges modulated by bulk pH with a possible influence on their lytic activity in lipid vesicles. The present study reports on a ... -
Impact of an antimicrobial peptide on the membrane fluidity of host membranes: influence of cholesterol and a hopanoid.
Alvares, D.; Ruggiero Neto, J. ; (European Biophysics Journal With Biophysics Letters, 2019) [Resumo]