• Application of Rare Earth Cation-Exchanged Nanozeolite as a Support for the Immobilization of Fungal Lipase and their Use in Biodiesel Production 

  de Paula Guarnieri, Guilherme ; de Vasconcellos, Adriano ; de Moraes, Fábio Rogério ; Nery, José Geraldo (Nano- and Biocatalysts for Biodiesel Production, 2021) [Capítulo de livro]

  For the last 50 years, zeolite ions exchanged with lanthanum (La3+) and cerium (Ce3+) rare earth cations have mostly been used as fluid catalytic cracking catalysts (FCCs) in the petrochemical industries for the production ...

• Brown Spider Venom Phospholipase-D Activity upon Different Lipid Substrates 

  Chaves-Moreira, Daniele; Gremski, Luiza Helena; de Moraes, Fábio Rogério ; Vuitika, Larissa; Wille, Ana Carolina Martins; Hernández González, Jorge Enrique ; Chaim, Olga Meiri; Senff-Ribeiro, Andrea; Arni, Raghuvir Krishnaswamy ; Veiga, Silvio Sanches (Toxins, 2023) [Artigo]

  Brown spider envenomation results in dermonecrosis, characterized by an intense inflammatory reaction. The principal toxins of brown spider venoms are phospholipase-D isoforms, which interact with different cellular membrane ...

• Exploring the Folding Mechanism of Dimeric Superoxide Dismutase 

  Mouro, Paulo R. ; Sanches, Murilo N. ; Leite, Vitor B. P. ; Chahine, Jorge (Journal of Physical Chemistry B, 2023) [Artigo]

  The Cu/Zn Human Superoxide Dismutase (SOD1) is a dimeric metalloenzyme whose genetic mutations are directly related to amyotrophic lateral sclerosis (ALS), so understanding its folding mechanism is of fundamental importance. ...

• Immunoprophylactic properties of the Corynebacterium pseudotuberculosis-derived MBP:PLD:CP40 fusion protein 

  Barral, Thiago Doria; Kalil, Mauricio Alcantara; Mariutti, Ricardo Barros ; Arni, Raghuvir Krishnaswamy ; Gismene, Carolina ; Sousa, Fernanda Severo; Collares, Tiago; Seixas, Fabiana Kommling; Borsuk, Sibele; Estrela-Lima, Alessandra et al. (Applied Microbiology and Biotechnology, 2022) [Artigo]

  Abstract: Caseous lymphadenitis (CLA) is a disease that affects small ruminants, and the best way to prevent its spread on a herd is through immunoprophylaxis. Thus, we aimed to evaluate the MBP:PLD:CP40 fusion protein as ...

• Probability distribution to obtain the characteristic passage time for different tri-stable potentials 

  Drigo Filho, Elso ; Chahine, Jorge ; Araujo, Marcelo Tozo; Ricotta, Regina Maria (Physica A: Statistical Mechanics and its Applications, 2022) [Artigo]

  The purpose of this work is to explore the kinetics of the transition probability distribution obtained as a solution to the Fokker–Planck equation (FPE) for a system described by a potential function (free energy) that ...

• Kinetic and structural studies of Mycobacterium tuberculosis dihydroorotate dehydrogenase reveal new insights into class 2 DHODH inhibition 

  Teixeira, Olívia; Martins, Ingrid Bernardes Santana ; Froes, Thamires Quadros; de Araujo, Alexandre Suman ; Nonato, Maria Cristina (Biochimica et Biophysica Acta - General Subjects, 2023) [Artigo]

  Tuberculosis (TB) is a leading cause of death worldwide. TB represents a serious public health threat, and it is characterized by high transmission rates, prevalence in impoverished regions, and high co-infection rates ...

• Out-of-plane deformability and its coupling with electrostatics in biomembranes 

  Wilke, Natalia; Alvares, Dayane S. (Emerging topics in life sciences, 2023) [Artigo]

  Cell membranes are quasi-bidimensional soft systems formed by multipoles in an ordered array that can be polarized in an electric field. Consequently, electrostatic potentials emerge inside membranes, and membranes respond ...

• Electrochemical sensor based on epoxy-functionalized BEA nanozeolite and graphene oxide modified glassy carbon electrode for bisphenol E determination 

  Miller, Alex H. ; Nguyen, Huong Thi-Thanh; Nery, José G. ; Fielding, Alistair J. (Journal of Applied Electrochemistry, 2023) [Artigo]

  An epoxy-functionalized beta type nanozeolite (BEA)/graphene oxide nanocomposite modified glassy carbon electrode (GCE/BEA/APTMS/GA/GO/NF) has been created for the differential pulse voltammetric determination of bisphenol ...

• Self-assembly of dengue virus empty capsid-like particles in solution 

  Neves-Martins, Thais C.; Mebus-Antunes, Nathane C.; Neto, Carlos H.G.; Barbosa, Glauce M.; Almeida, Fabio C.L.; Caruso, Icaro P. ; Da Poian, Andrea T. (iScience, 2023) [Artigo]

  Nucleocapsid (NC) assembly is an essential step of the virus replication cycle. It ensures genome protection and transmission among hosts. Flaviviruses are human viruses for which envelope structure is well known, whereas ...

• The influence of pH on the structure and stability of the Grb2 dimer reveals changes in the inter-domain and molecular interaction: Could it be a modulation mechanism? 

  Tedesco, Jéssica A. ; Dias, Raphael V.R. ; Casteluci, Giovana ; Pedro, Renan P. ; de Oliveira, Leandro C. ; Caruso, Ícaro P. ; Melo, Fernando A. (Biophysical Chemistry, 2023) [Artigo]

  Cancer cells present an increased replicative potential as a hallmark. The increased replication leads to a higher intracellular pH. Grb2, an adapter protein, is mainly involved in several types of cancers due to its role ...

• An adsorption agent based on chitosan-zeolite composite: environmental and radioactive liquid waste remediation 

  de Araujo, Leandro Goulart; Medeiros, Vinicius Litrenta ; Guarnieri, Guilherme de Paula ; da Silva, Danilo Antonio ; Watanabe, Tamires; Marumo, Júlio Takehiro; Nery, José Geraldo (Environmental Science: Advances, 2023) [Artigo]

  In this article, we present a chitosan-zeolite composite, which was synthesized and used as an adsorbent material for caesium (Cs) removal from aqueous media and real liquid radioactive organic waste (LROW). The compound ...

• Interphase chromosomes of the Aedes aegypti mosquito are liquid crystalline and can sense mechanical cues 

  Contessoto, Vinícius G. ; Dudchenko, Olga; Aiden, Erez Lieberman; Wolynes, Peter G.; Onuchic, José N.; Di Pierro, Michele (Nature Communications, 2023) [Artigo]

  We use data-driven physical simulations to study the three-dimensional architecture of the Aedes aegypti genome. Hi-C maps exhibit both a broad diagonal and compartmentalization with telomeres and centromeres clustering ...

• Syntheses of novel topical hemostatic agents based on pectin biopolymer aiming hemorrhage control: Thromboelastographic studies and non-homogeneous swelling effect 

  Santisteban, Oscar A.N. ; Sacco, Guilherme M. ; Guarnieri, Guilherme De Paula ; Godoy, Moacir Fernandes de; Azevedo, Eduardo Ribeiro de; Nery, José Geraldo (Materials Today Communications, 2022) [Artigo]

  Topical hemostatic agents based on pectin biopolymer were synthesized and characterized by X-ray diffraction (XRD), Scanning Electronic Microscopy (SEM), Phase Contrast Microscopy, Infrared spectroscopy (FT-IR), Differential ...

• Transcriptomic Profiling of Rectus Abdominis Muscle in Women with Gestational Diabetes-Induced Myopathy: Characterization of Pathophysiology and Potential Muscle Biomarkers of Pregnancy-Specific Urinary Incontinence 

  Alves, Fernanda Cristina Bergamo ; Oliveira, Rafael Guilen de ; Reyes, David Rafael Abreu ; Garcia, Gabriela Azevedo ; Floriano, Juliana Ferreira ; Shetty, Raghavendra Hallur Lakshmana ; Mareco, Edson Assunção; Dal-Pai-Silva, Maeli ; Payão, Spencer Luiz Marques; Souza, Fátima Pereira de et al. (International Journal of Molecular Sciences, 2022) [Artigo]

  Gestational diabetes mellitus (GDM) is recognized as a “window of opportunity” for the future prediction of such complications as type 2 diabetes mellitus and pelvic floor muscle disorders, including urinary incontinence ...

• Structure-Function Relationship in Heterodimeric Neurotoxin PLA2s from Viperidae Snakes Inhabiting Europe, South America, and Asia Functional Importance of the Nontoxic Components 

  Georgieva, Dessislava; Arni, Raghuvir K. ; Betzel, Christian; Calvete, J. J.; Gopalakrishnakone, P. (Venom Genomics And Proteomics, 2016) [Artigo]

  Snake venom heterodimeric non-covalent phospholipase A(2) (PLA(2)) complexes (ncHdPLA(2)s) are neurotoxins encountered in the venoms of Viperinae and Crotalinae snakes. In contrast to their monomeric counterparts, they ...

• Three-Dimensional Structures and Mechanisms of Snake Venom Serine Proteinases, Metalloproteinases, and Phospholipase A(2)s 

  Coronado, M. A. ; Moraes, F. R. de ; Ullah, A. ; Masood, R. ; Santana, V. S. ; Mariutti, R. ; Brognaro, H. ; Georgieva, Dessislava; Murakami, M. T.; Betzel, Christian et al. (Venom Genomics And Proteomics, 2016) [Artigo]

  High-resolution crystal structures provide accurate information of the positions of the atoms which can be used to understand substrate specificity, secondary binding sites, and catalytic mechanisms. Detailed structural ...

• Properties of high-performance solution-processed transparent thin film transistors 

  De Lima, Guilherme Rodrigues; Braga, João Paulo; Santos, Lucas Fugikawa; Gozzi, Giovani Fornereto (2019) [Dado de pesquisa]

• A Computational–Experimental Investigation of the Molecular Mechanism of Interleukin-6-Piperine Interaction 

  Povinelli, Ana Paula Ribeiro; Zazeri, Gabriel; Jones, Alan M.; Cornélio, Marinônio Lopes (International Journal of Molecular Sciences, 2022) [Artigo]

  Herein, we elucidate the biophysical aspects of the interaction of an important protein, Interleukin-6 (IL6), which is involved in cytokine storm syndrome, with a natural product with anti-inflammatory activity, piperine. ...

• Biophysical studies of the interaction of hRSV Non-Structural 1 protein with natural flavonoids and their acetylated derivatives by spectroscopic techniques and computational simulations 

  Ottenio de Lourenço, Isabella ; Toscano Pedroso Quintino, Evelyn ; Henrique Pereira, Matheus ; Sprengel Lima, Caroline ; Campos Araújo, Gabriela ; Octávio Regasini, Luis ; Alves de Melo, Fernando ; Pereira de Souza, Fátima ; Andres Fossey, Marcelo ; Putinhon Caruso, Ícaro (Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2022) [Artigo]

  Human respiratory syncytial virus (hRSV) infections are one of the most causes of acute lower respiratory tract infections in children and elderly. The development of effective antiviral therapies or preventive vaccines ...

• Aqueous mixtures of cornstarch and Pluronic® F127 studied by experimental and computational techniques 

  Baldassa, Monize A.B. ; Dias, Raphael V.R. ; Oliveira, Leandro C. ; Feitosa, Eloi (Food Research International, 2022) [Artigo]

  The possibility of interaction between cornstarch (CS) and amphiphilic molecules, such as the micelle-forming triblock copolymer Pluronic® F127 (F127), also known by Poloxamer 407, indicates that CS-F127 aqueous mixtures ...

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