Now showing items 1-3 of 3
Recent advances in the understanding of brown spider venoms: From the biology of spiders to the molecular mechanisms of toxins
(Toxicon, 2014-06-01) [Artigo]
The Loxosceles genus spiders (the brown spiders) are encountered in all the continents, and the clinical manifestations following spider bites include skin necrosis with gravitational lesion spreading and occasional systemic ...
Crystallization and preliminary X-ray diffraction analysis of a novel sphingomyelinase D from Loxosceles gaucho venom
(Acta Crystallographica Section F-structural Biology Communications, 2014-10-01) [Artigo]
Brown spider envenomation results in dermonecrosis, intravascular coagulation, haemolysis and renal failure, mainly owing to the action of sphingomyelinases D (SMases D), which catalyze the hydrolysis of sphingomyelin to ...
Crystallization and preliminary X-ray diffraction studies of an L-amino-acid oxidase from Lachesis muta venom
(Acta Crystallographica Section F-structural Biology Communications, 2014-11-01) [Artigo]
Snake-venom proteins form multi-component defence systems by the recruitment and rapid evolution of nonvenomous proteins and hence serve as model systems to understand the structural modifications that result in toxicity. ...