Now showing items 1-4 of 4
Modeling and molecular dynamics indicate that snake venom phospholipase B-like enzymes are Ntn-hydrolases
(Toxicon, 2018-10-01) [Resenha]
Phospholipase-B-like (SVPLB-like) enzymes are present in relatively small amounts in a number of venoms, however, their biological function and mechanisms of action are un-clear. A three-dimensional model of the SVPLB-like ...
Lipid-packing perturbation of model membranes by pH-responsive antimicrobial peptides
(Biophysical Reviews, 2017-10-01) [Resenha]
The indiscriminate use of conventional antibiotics is leading to an increase in the number of resistant bacterial strains, motivating the search for new compounds to overcome this challenging problem. Antimicrobial peptides, ...
Molecular Aspects of the Dengue Virus Infection Process: A Review
(Protein And Peptide Letters, 2018-01-01) [Resenha]
Background: At the present time, dengue is one of the most important arboviruses affecting man, becoming a serious global public health problem, especially in subtropical and tropical countries, where environmental conditions ...
Brown spider (Loxosceles) venom toxins as potential biotools for the development of novel therapeutics
(Toxins, 2019-06-01) [Resenha]
Brown spider envenomation results in dermonecrosis with gravitational spreading characterized by a marked inflammatory reaction and with lower prevalence of systemic manifestations such as renal failure and hematological ...