Now showing items 1-2 of 2
Molecular model of cyclin-dependent kinase 5 complexed with roscovitine
(Biochemical and Biophysical Research Communications, 2002-10-11) [Artigo]
Here is described a structural model for the binary complex CDK5-roscovitine. Roscovitine has been shown to potently inhibit cyclin-dependent kinases 1, 2 and 5 (CDK1, 2, and 5), and the structure of CDK2 complexed with ...
Molecular model of shikimate kinase from Mycobacterium tuberculosis
(Biochemical and Biophysical Research Communications, 2002-07-18) [Artigo]
Tuberculosis (TB) resurged in the late 1980s and now kills approximately 3 million people a year. The reemergence of tuberculosis as a public health threat has created a need to develop new anti-mycobacterial agents. The ...