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dc.contributor.authorAfonso Camargo, Samira Esteves
dc.contributor.authorRode, Sigmar de Mello [UNESP]
dc.contributor.authordo Prado, Renata Falchete [UNESP]
dc.contributor.authorCarvalho, Yasmin Rodarte
dc.contributor.authorRibeiro Camargo, Carlos Henrique [UNESP]
dc.date.accessioned2014-05-20T14:04:24Z
dc.date.available2014-05-20T14:04:24Z
dc.date.issued2010-05-01
dc.identifierhttp://dx.doi.org/10.1590/S1678-77572010000300014
dc.identifier.citationJournal of Applied Oral Science. Bauru-sp: Univ São Paulo Fac Odontologia Bauru, v. 18, n. 3, p. 273-278, 2010.
dc.identifier.issn1678-7757
dc.identifier.urihttp://hdl.handle.net/11449/22596
dc.description.abstractCastor oil bean cement (COB) is a new material that has been used as an endodontic sealer, and is a candidate material for direct pulp capping. Objective: The purpose of this study was to evaluate the biocompatibility of a new formulation of COB compared to calcium hydroxide cement (CH) and a control group without any material, in the subcutaneous tissue of rats. Material and Methods: The materials were prepared, packed into polyethylene tubes, and implanted in the rat dorsal subcutaneous tissue. Animals were sacrificed at the 7th and 50th days after implantation. A quantitative analysis of inflammatory cells was performed and data were subjected to ANOVA and Tukey's tests at 5% significance level. Results: Comparing the mean number of inflammatory cells between the two experimental groups (COB and CH) and the control group, statistically significant difference (p=0.0001) was observed at 7 and 50 days. There were no significant differences (p=0.111) between tissue reaction to CH (382 inflammatory cells) and COB (330 inflammatory cells) after 7 days. After 50 days, significantly more inflammatory cells (p=0.02) were observed in the CH group (404 inflammatory cells) than in the COB group (177 inflammatory cells). Conclusions: These results demonstrate that the COB cement induces less inflammatory response within long periods.en
dc.format.extent273-278
dc.language.isoeng
dc.publisherUniversidade de São Paulo (USP), Faculdade de Odontologia de Bauru
dc.relation.ispartofJournal of Applied Oral Science
dc.sourceWeb of Science
dc.subjectCalcium hydroxideen
dc.subjectCastor oilen
dc.subjectPulp cappingen
dc.subjectRatsen
dc.titleSubcutaneous tissue reaction to castor oil bean and calcium hydroxide in ratsen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/jaos/paboutj.htm
dcterms.rightsHolderUniv São Paulo Fac Odontologia Bauru
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionSuper Sch Cruzeiro
dc.description.affiliationUNESP, Dept Biociencias & Diag Bucal, Fac Odontol Sao Jose dos Campos, Sao Jose dos Campos Dent Sch, BR-12245000 Sao Jose Dos Campos, Brazil
dc.description.affiliationUNESP, Dept Dent Mat & Prosthodont, Sao Jose dos Campos Dent Sch, BR-12245000 Sao Jose Dos Campos, Brazil
dc.description.affiliationSuper Sch Cruzeiro, Dept Physiotherapy, Cruzeiro, SP, Brazil
dc.description.affiliationUNESP, Dept Restorat Dent, Sao Jose dos Campos Dent Sch, BR-12245000 Sao Jose Dos Campos, Brazil
dc.description.affiliationUnespUNESP, Dept Biociencias & Diag Bucal, Fac Odontol Sao Jose dos Campos, Sao Jose dos Campos Dent Sch, BR-12245000 Sao Jose Dos Campos, Brazil
dc.description.affiliationUnespUNESP, Dept Dent Mat & Prosthodont, Sao Jose dos Campos Dent Sch, BR-12245000 Sao Jose Dos Campos, Brazil
dc.description.affiliationUnespUNESP, Dept Restorat Dent, Sao Jose dos Campos Dent Sch, BR-12245000 Sao Jose Dos Campos, Brazil
dc.identifier.scieloS1678-77572010000300014
dc.identifier.wosWOS:000281692000013
dc.rights.accessRightsAcesso aberto
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Ciência e Tecnologia, São José dos Campospt
dc.identifier.fileS1678-77572010000300014.pdf
dc.identifier.lattes3422118958429909
dc.identifier.lattes6967369119792151
unesp.author.lattes3422118958429909
unesp.author.lattes6967369119792151
unesp.author.orcid0000-0002-4261-4217[2]
dc.relation.ispartofjcr1.709
dc.relation.ispartofsjr0,645
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