Evaluation of different media for the production of cephalosporins by Streptomyces clavuligerus ATCC 27064
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Data
2012-12-01
Autores
Antonio, Tatiana [UNESP]
Bellão, Carolina
Corrêa, Tatiana [UNESP]
Cavallieri, André Pastrelo [UNESP]
Badino, Alberto Colli
Araujo, Maria Lucia Gonsales da Costa [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Brazilian Archives of Biology and Technology
Resumo
The aim of this work was to compare the composition of a complex and soluble culture medium to eight other media described in the literature through the batch cultivation in a conventional bench-scale bioreactor for the production of cephamycin C by a wild strain of Streptomyces clavuligerus. The proposed medium resulted in an antibiotic production 1.5 to 7.5 times higher than the other culture media.
Descrição
Palavras-chave
β-lactam antibiotic, Streptomyces clavuligerus, lysine metabolism, complex medium
Como citar
Brazilian Archives of Biology and Technology. Brazilian Archives of Biology and Technology, v. 55, n. 6, p. 819-825, 2012.