Cobalt phthalocyanine as a biomimetic catalyst in the amperometric quantification of dipyrone using FIA

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Data

2011-09-30

Autores

Boni, Ana Carolina [UNESP]
Wong, Ademar [UNESP]
Fireman Dutra, Rosa Amalia
Taboada Sotomayor, Maria Del Pilar [UNESP]

Título da Revista

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Editor

Elsevier B.V.

Resumo

A biomimetic sensor for the determination of dipyrone was prepared by modifying carbon paste with cobalt phthalocyanine (CoPc), and used as an amperometric detector in a flow injection analysis (FIA) system. The results of cyclic voltammetry experiments suggested that CoPc behaved as a biomimetic catalyst in the electrocatalytic oxidation of dipyrone, which involved the transfer of one electron. The optimized FIA procedure employed a flow rate of 1.5 mL min(-1), a 75 mu L sample loop, a 0.1 mol L-1 phosphate buffer carrier solution at pH 7.0 and amperometric detection at a potential of 0.3 V vs. Ag/AgCl. Under these conditions, the proposed method showed a linear response for dipyrone concentrations in the range 5.0 x 10(-6)-6.3 x 10(-3) mol L-1. Selectivity and interference studies were carried out in order to validate the system for use with pharmaceutical and environmental samples. In addition to being environmentally friendly, the proposed method is a sensitive and selective analytical tool for the determination of dipyrone. (C) 2011 Elsevier B.V. All rights reserved.

Descrição

Palavras-chave

Biomimetic catalyst, Cobalt phthalocyanine, Dipyrone, Flow injection system

Como citar

Talanta. Amsterdam: Elsevier B.V., v. 85, n. 4, p. 2067-2073, 2011.