Now showing items 31-40 of 49
Role of Locus coeruleus noradrenergic neurons in cardiorespiratory and thermal control during hypoxia
(Respiratory Physiology & Neurobiology, 2010-02-28) [Artigo]
We investigated the specific role of LC noradrenergic (NA) neurons in the cardiorespiratory and thermal responses to hypoxia. Aiming this, LC NA neurons were selectively destroyed by microinjecting 6-OHDA bilaterally in ...
Cardiorespiratory effects of gap junction blockade in the locus coeruleus in unanesthetized adult rats
(Respiratory Physiology & Neurobiology, 2014-01-01) [Artigo]
The locus coeruleus (LC) plays an important role in central chemoreception. In young rats (P9 or younger), 85% of LC neurons increase firing rate in response to hypercapnia vs. only about 45% of neurons from rats P10 or ...
Periaqueductal gray matter modulates the hypercapnic ventilatory response
(Pflugers Archiv: European Journal of Physiology, 2012-08-01) [Artigo]
The periaqueductal gray (PAG) is a midbrain structure directly involved in the modulation of defensive behaviors. It has direct projections to several central nuclei that are involved in cardiorespiratory control. Although ...
Cardiorespiratory responses to hypercapnia in chickens after embryonic exposure to CO2
(FASEB Journal, 2013-04-01) [Resumo]
Hypoxia during embryonic development increases energy metabolism in normoxic juvenile chicks
(Comparative Biochemistry And Physiology A-molecular & Integrative Physiology, 2017-05-01) [Artigo]
Environmental changes during perinatal development can affect the postnatal life. In this sense, chicken embryos that experience low levels of O-2 over a specific phase of incubation can have their tissue growth reduced ...
The Role of Ca2+ and BK Channels of Locus Coeruleus (LC) Neurons as a Brake to the CO2 Chemosensitivity Response of Rats
(Neuroscience, 2018-06-15) [Artigo]
The cellular mechanisms by which LC neurons respond to hypercapnia are usually attributed to an “accelerator” whereby hypercapnic acidosis causes an inhibition of K+ channels or activation of Na+ and Ca+2 channels to ...
Ionotropic glutamatergic receptors in the rostral medullary raphe modulate hypoxia and hypercapnia-induced hyperpnea
(Respiratory Physiology & Neurobiology, 2011-01-31) [Artigo]
It has been suggested that the medullary raphe (MR) plays a key role in the physiological responses to hypoxia and hypercapnia. We assessed the role of ionotropic glutamate receptors in the rostral MR (rMR) in the respiratory ...
Opioid mu-receptors in the rostral medullary raphe modulate hypoxia-induced hyperpnea in unanesthetized rats
(FASEB Journal, 2012-04-01) [Resumo]
Serotonergic neurons in the nucleus raphe obscurus contribute to interaction between central and peripheral ventilatory responses to hypercapnia
(Pflugers Archiv: European Journal of Physiology, 2011-09-01) [Artigo]
Serotonergic (5-HT) neurons in the nucleus raphe obscurus (ROb) are involved in the respiratory control network. However, it is not known whether ROb 5-HT neurons play a role in the functional interdependence between central ...
The locus coeruleus and central chemosensitivity
(Respiratory Physiology & Neurobiology, 2010-10-31) [Artigo]
The locus coeruleus (LC) lies in the dorsal pons and supplies noradrenergic (NA) input to many regions of the brain, including respiratory control areas. The LC may provide tonic input for basal respiratory drive and is ...