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Role of preoptic opioid receptors in the body temperature reduction during hypoxia
(Brain Research, 2009-08-25) [Artigo]
Evidence indicates that endogenous opioids play a role in body temperature (Tb) regulation in mammals but no data exist about the involvement of the specific opioid receptors, mu, kappa and delta, in the reduction of Tb ...
Serotonergic mechanisms on breathing modulation in the rat locus coeruleus
(Pflugers Archiv: European Journal of Physiology, 2010-02-01) [Artigo]
The locus coeruleus (LC) is a noradrenergic nucleus that plays an important role in the ventilatory response to hypercapnia. This nucleus is densely innervated by serotonergic fibers and contains high density of serotonin ...
ATP in the locus coeruleus as a modulator of cardiorespiratory control in unanaesthetized male rats
(Experimental Physiology, 2014-01-01) [Artigo]
Locus coeruleus (LC) noradrenergic neurons are chemosensitive to CO2 and pH in mammals and amphibians and are involved in the CO2-related drive to breathe. Purinergic neuromodulation in the LC is of particular interest ...
Serotonergic neurons in the nucleus raphé obscurus are not involved in the ventilatory and thermoregulatory responses to hypoxia in adult rats
(Respiratory Physiology and Neurobiology, 2013-06-15) [Artigo]
The medullary raphé is an important component of the central respiratory network, playing a key role in CO2 central chemoreception. However, its participation in hypoxic ventilatory responses is less understood. In the ...
Role of brain nitric oxide in the cardiovascular control of bullfrogs
(Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology, 2013-06-01) [Artigo]
The goal of the present study was to determine if nitric oxide (NO) acting on the brain of bullfrog (Lithobates catesbeianus) is involved in arterial pressure and heart rate (HR) control by influencing sympathetic activity. ...
The breathing pattern and the ventilatory response to aquatic and aerial hypoxia and hypercarbia in the frog Pipa carvalhoi
(Comparative Biochemistry and Physiology A-molecular & Integrative Physiology, 2012-07-01) [Artigo]
Anuran amphibians are known to exhibit an intermittent pattern of pulmonary ventilation and to exhibit an increased ventilatory response to hypoxia and hypercarbia. However, only a few species have been studied to date. ...
Role of central nitric oxide in behavioral thermoregulation of toads during hypoxia
(Physiology & Behavior, 2008-09-03) [Artigo]
Nitric oxide (NO) is thought to play a key role in the development of hypoxia-induced anapyrexia in mammals, acting on the preoptic region of the anterior hypothalamus to activate autonomic heat loss responses. Regarding ...
Locus coeruleus noradrenergic neurons and CO2 drive to breathing
(Pflugers Archiv: European Journal of Physiology, 2008-03-01) [Artigo]
The Locus coeruleus (LC) has been suggested as a CO2 chemoreceptor site in mammals. In the present study, we assessed the role of LC noradrenergic neurons in the cardiorespiratory and thermal responses to hypercapnia. To ...
Role of Locus coeruleus noradrenergic neurons in cardiorespiratory and thermal control during hypoxia
(Respiratory Physiology & Neurobiology, 2010-02-28) [Artigo]
We investigated the specific role of LC noradrenergic (NA) neurons in the cardiorespiratory and thermal responses to hypoxia. Aiming this, LC NA neurons were selectively destroyed by microinjecting 6-OHDA bilaterally in ...
Cardiorespiratory effects of gap junction blockade in the locus coeruleus in unanesthetized adult rats
(Respiratory Physiology & Neurobiology, 2014-01-01) [Artigo]
The locus coeruleus (LC) plays an important role in central chemoreception. In young rats (P9 or younger), 85% of LC neurons increase firing rate in response to hypercapnia vs. only about 45% of neurons from rats P10 or ...