RSS 1.0Departamento de Química Orgânica
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Antinociceptive, anti-inflammatory and gastroprotective effects of a hydroalcoholic extract from the leaves of Eugenia punicifolia (Kunth) DC. in rodents
Basting, Rosanna T.
; Nishijima, Catarine M. ; Lopes, Juliana A. ; Santos, Raquel C. ; Perico, Larissa Lucena ; ; ; Costa, Miriam F. ; Santos, Lourdes C. ; Rocha, Lucia R. M. et al. (Journal of Ethnopharmacology, 2014) [Artigo]
Ethnopharmacological relevance: An ethnopharmacological survey indicated that leaves from Eugenia punicifolia (Kunth) DC. (Myrtaceae) are popularly used as a natural therapeutic agent to treat pain and inflammation. Aim ... -
Conservação e uso sustentável da diversidade vegetal do Cerrado e da Mata Atlântica : diversidade química e prosecção de novas drogas
Bolzani, Vanderlan da Silva (Congresso de Extensão Universitária, 2001) [Resumo]
As plantas produzem metabólitos secundários (produtos naturais) que desempenham um papel importante em sua defesa contra patógenos e outros predadores. Alguns desses produtos naturais são também utilizados na medicina, na ... -
21 anos de história do grupo alquimia
Perazolli, Leinig Antonio; Jafelicci Junior, Miguel ; Davolos, Marian Rosaly ; Sotomayor, Maria Del Pilar Taboada ; Oliveira, José Eduardo de ; Pezza, Leonardo (Congresso de Extensão Universitária, 2009) [Resumo]
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Programa de conscientização da população sobre o impacto ambiental do descarte inadequado de medicamentos vencidos e proposição de soluções
Pezza, Helena Redigolo; Saraiva, Lívia Miron ; Alamino, Andreza de França ; Spadoto, Mariane ; Ferreira, Andrielly Steffany Santos ; Silva, Márcia Cristina da ; Nogueira, Raquel Fernandes Pupo ; Pezza, Leonardo (Congresso de Extensão Universitária, 2013) [Trabalho apresentado em evento]
O consumo de medicamentos sofreu um aumento significativo nos últimos anos em decorrência do crescimento da população e disseminação de doenças. No Brasil, os medicamentos não são comercializados na forma fracionada e até ... -
Avaliação de comunicações de invenção pela agência Unesp de Inovação
Spiandorello, Fabíola de Moraes; Kopp, Vitor Garcia ; Bolzani, Vanderlan da Silva (Congresso de extensão universitária da UNESP, 2015) [Trabalho apresentado em evento]
Agência Unesp de Inovação – AUIN is Unesp’s technology transfer office, being responsible for taking actions in order to protect the inventions developed by its faculty members and students. In this work, we seek to elucidate ... -
Germination of Cochlospermum regium Seeds: Influence of Seed Size, Vials, Vial Sealing In vitro, and Substrate In vivo
; ; ; Pereira, Ana Maria Soares (European Journal of Medicinal Plants, 2015) [Artigo]
Aims: This work aimed to assess how seed size, vials, vial sealing (in vitro), and substrate (in vivo) affect C. regium germination and emergence. This study shall contribute to the viable production of C. regium seedlings. ... -
Antiulcerogenic activity of the aqueous fraction of Anacardium humile St. Hil (Anacardiaceae)
; ; ; Hiruma-Lima, Clélia Akiko; Santos, Lourdes Campaner dos ; Vilegas, Wagner ; (Journal of Medicinal Plant Research, 2012) [Artigo]
Anacardium humile St. Hil. is being used in traditional medicine to treat ulcer. The present work evaluated the mechanisms of action involved in the anti-ulcer properties of the aqueous fraction from leaves of A. humile ... -
Inhibitory effect of gallic acid and its esters on 2,2'-azobis(2-amidinopropane)hodrpchloride (AAPH)-induced hemolysis and depletion of intracellular glutathione in erythrocytes
Ximenes, Valdecir Farias; Lopes, Mariana G. ; Petrônio, Maicon Segalla ; Regasini, Luis Octavio ; Silva, Dulce Helena Siqueira ; Fonseca, Luiz Marcos da (Journal of Agricultural and Food Chemistry, 2010) [Artigo]
The protective effect of gallic acid and its esters, methyl, propyl, and lauryl gallate, against 2,2'-azobis(2-amidinopropane)hydrochloride (AAPH)-induced hemolysis and depletion of intracellular glutathione (GSH) in ... -
Redox-active biflavonoids from Garcinia brasiliensis as inhibitors of neutrophil oxidative burst and human erythrocyte membrane damage
Arwa, Phanuel Saroni; Zeraik, Maria Luiza ; Farias Ximenes, Valdecir ; Fonseca, Luiz Marcos da ; Bolzani, Vanderlan da Silva ; Siqueira Silva, Dulce Helena (Journal Of Ethnopharmacology, 2015) [Artigo]
Garcinia brasiliensis, a plant native to the Brazilian Amazon Rainforest, is used in traditional medicine to treat inflammation of the urinary tract, peptic ulcers, arthritis and other conditions. The purposes of this study ... -
Synthesis and evaluation of novel prenylated chalcone derivatives as anti-leishmanial and anti-trypanosomal compounds
Passalacqua, Thais Gaban; Dutra, Luiz Antonio ; Almeida, Letícia de ; Velásquez, Angela Maria Arenas ; Torres, Fábio Aurélio Esteves ; Yamasaki, Paulo Renato ; Santos, Mariana Bastos dos ; Regasini, Luis Octavio ; ; Bolzani, Vanderlan da Silva et al. (Bioorganic and Medicinal Chemistry Letters, 2015) [Artigo]
Chalcones form a class of compounds that belong to the flavonoid family and are widely distributed in plants. Their simple structure and the ease of preparation make chalcones attractive scaffolds for the synthesis of a ... -
Coffee adulteration: more than two decades of research
Toci, Aline Theodoro; ; Pezza, Helena Redigolo ; Pezza, Leonardo (Critical Reviews in Analytical Chemistry/Crc, 2015) [Artigo]
Abstract Coffee is a ubiquitous food product of considerable economic importance to the countries that produce and export it. The adulteration of roasted coffee is a strategy used to reduce costs. Conventional methods ... -
Nanostructured lipid system as a strategy to improve the anti-Candida albicans activity of Astronium sp
Bonifácio, Bruna Vidal; Ramos, Matheus Aparecido dos Santos ; Silva, Patrícia Bento da ; Negri, Kamila Maria Silveira ; Oliveira Lopes, Érica de ; Souza, Leonardo Perez de ; Vilegas, Wagner ; Pavan, Fernando Rogério ; Chorilli, Marlus ; Bauab, Taís Maria (International Journal Of Nanomedicine, 2015) [Artigo]
The genus Astronium (Anacardiaceae) includes species, such as Astronium fraxinifolium, Astronium graveolens, and Astronium urundeuva, which possess anti-inflammatory, anti-ulcerogenic, healing, and antimicrobial properties. ... -
Mutagenicity and chemopreventive activities of Astronium species assessed by Ames test
Resende, Flávia Aparecida; Campos, Debora Leite ; da Silva, Viviane Cândida ; Grandis, Rone Aparecido de ; Souza, Leonardo Perez ; Leonardo Junior, Carlos Sérgio ; da Rocha, Cláudia Quintino ; dos Santos, Lourdes Campaner ; Vilegas, Wagner ; Varanda, Eliana Aparecida (Regulatory Toxicology And Pharmacology : Rtp, 2015) [Artigo]
In the neotropical savannah, Astronium species are used in popular medicine to treat allergies, inflammation, diarrhea and ulcers. Given that natural products are promising starting points for the discovery of novel ... -
Antifungals and acetylcholinesterase inhibitors from the stem bark of Croton heliotropiifolius
Queiroz, Marcos Marçal Ferreira; ; Zeraik, Maria Luiza ; Marti, G. ; ; ; ; ; ; et al. (Phytochemistry Letters, 2014) [Artigo]
The ethanolic extract of the stem bark of Croton heliotropiifolius Kunth (Euphorbiaceae) showed significant in vitro inhibition of acetylcholinesterase using a dilution spectrophotometric assay and antifungal activity ... -
Two decades of research on natural products chemistry from Brazilian biodiversity: inspirations and motivations
Bolzani, Vanderlan (Abstracts Of Papers Of The American Chemical Society, 2014) [Resumo]
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Trade off between separation, detection, and sustainability in liquid chromatographic fingerprinting
Funari, Cristiano Soleo de; ; Cavalheiro, Alberto José ; ; (Abstracts Of Papers Of The American Chemical Society, 2014) [Resumo]
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Photoelectrochemical reduction of CO2 on Cu/Cu2O films: Product distribution and pH effects
Brito, Juliana Ferreira de; Araujo, Angela Regina ; ; Zanoni, Maria Valnice Boldrin (Chemical Engineering Journal, 2015) [Artigo]
This work focuses on photoelectrochemical CO2 reduction at a Cu/Cu2O electrode (1 x 1 cm(2)). The formation of methanol, ethanol, formaldehyde, acetaldehyde, and acetone was monitored during UV-visible radiation for 3 h ... -
Acetone as a greener alternative to acetonitrile in liquid chromatographic fingerprinting
Funari, Cristiano Soleo; ; ; Cavalheiro, Alberto Jose ; (Journal Of Separation Science, 2015) [Artigo]
A considerable amount of chemical waste from liquid chromatography analysis is generated worldwide. Acetonitrile is the most employed solvent in liquid chromatography analyses since it exhibits favorable physicochemical ... -
Ribifolin, an orbitide from jatropha ribifolia, and its potential antimalarial activity
Pinto, Meri Emili F.; Batista, Joao M. ; ; ; ; ; Cilli, Eduardo Maffud ; ; ; et al. (Journal Of Natural Products, 2015) [Artigo]
A new orbitide named ribifolin was isolated and characterized from Jatropha ribifolia using mass spectrometry, NMR spectroscopy, quantitative amino acid analysis, molecular dynamics/simulated annealing, and Raman optical ... -
Hydrophobicity and antioxidant activity acting together for the beneficial health properties of nordihydroguaiaretic acid
Paracatu, Luana Chiquetto; Quinello Gomes de Faria, Carolina Maria ; Zeraik, Maria Luiza ; ; ; ; Fonseca, Luiz Marcos da ; Ximenes, Valdecir Farias (Food &function, 2015) [Artigo]
Nordihydroguaiaretic acid (NDGA) and rosmarinic acid (RA), phenolic compounds found in various plants and functional foods, have known antioxidant and anti-inflammatory properties. In the present study, we comparatively ...