Now showing items 1-2 of 2
Isolation, leishmanicidal evaluation and molecular docking simulations of piperidine alkaloids from Senna spectabilis
(Bioorganic & Medicinal Chemistry, 2018-12-01) [Artigo]
Leishmaniasis is one of the most important neglected tropical diseases (NTDs) that are especially common among low-income populations in developing regions of Africa, Asia, and the Americas. Many natural products, particularly ...
Alkaloids derived from flowers of Senna spectabilis, (-)-cassine and (-)-spectaline, have antiproliferative activity on HepG2 cells for inducing cell cycle arrest in G1/S transition through ERK inactivation and downregulation of cyclin D1 expression
(Toxicology In Vitro, 2016-03-01) [Artigo]
Cancer is one of the most critical problems of public health in the world and one of the main challenges for medicine in this century. Unfortunately, most patients are diagnosed at advanced stage, when the treatment options ...