Now showing items 1-2 of 2
Molecular hybridization: A useful tool in the design of new drug prototypes
(Current Medicinal Chemistry, 2007-07-01) [Resenha]
Molecular hybridization is a new concept in drug design and development based on the combination of pharmacophoric moieties of different bioactive substances to produce a new hyrid compound with improved affinity and ...
New anti-Alzheimer drugs from biodiversity: the role of the natural acetylcholinesterase inhibitors
(Mini-Reviews in Medicinal Chemistry, 2005-10-01) [Resenha]
Alzheimer's disease (AD) is a progressive neurodegenerative pathology with severe economic and social impact. There is currently no cure, although cholinesterase inhibitors provide effective temporary relief of symptoms ...