Now showing items 1-10 of 25
Vernonia polyanthes as a new source of antiulcer drugs
(Fitoterapia, 2007-12-01) [Artigo]
Methanolic (VPME) and chloroformic (VPCL) extracts, obtained from the aerial parts of Vernonia polyanthes, were investigated for its antiulcerogenic properties. Administration of VPME (250 mg/kg) and VPCL (50 mg/kg) ...
Bioprospecção de atividade antioxidante e antimicrobiana da casca de Stryphnodendron adstringens (Mart.) Coville (Leguminosae-Mimosoidae)
(Revista de Ciências Farmacêuticas Básica e Aplicada, 2007-12-01) [Artigo]
The aim of this work was to evaluate the class of secondary metabolites responsible for the antioxidant and antimicrobial activities of bark extracts of Stryphnodendron adstringens (Mart.) Coville (Leguminosae-Mimosoidae), ...
A new ent-kaurane diterpene from stems of Alibertia macrophylla K. Schum. (Rubiaceae)
(Helvetica Chimica Acta, 2007-10-11) [Artigo]
Phytochemical investigations of the stems of a specimen of Alibertia macrophylla led to the isolation and characterization of the new diterpene ent-kaurane-2β,3α,16α-triol (1), along with triterpenes 2-8, iridoids 9-12, ...
Separation of the toxic zierin from Zollernia ilicifolia by high speed countercurrent chromatography
(Revista Brasileira de Plantas Medicinais, 2007-11-01) [Artigo]
Preliminary pharmacological assays of the 70% methanol extract from the leaves of the Brazilian medicinal plant Zollernia ilicifolia Vog. (Fabaceae) showed analgesic and antiulcerogenic effects. Previous analyses have shown ...
Fast preparative separation of flavones from capitula of Eriocaulon ligulatum (Vell.) L.B.Smith (Eriocaulaceae) by High-speed countercurrent chromatography (HSCCC)
(Revista de Ciências Farmacêuticas Básica e Aplicada, 2005-12-01) [Artigo]
High-speed countercurrent chromatography (HSCCC) is a leading method for the fast separation of natural products from plants. It was used for the preparative isolation of two flavone monoglucosides present in the capitula ...
Microbial transformation of cadina-4,10(15)-dien-3-one, aromadendr-1(10)-en-9-one and methyl ursolate by Mucor plumbeus ATCC 4740
(Phytochemistry, 2002-03-04) [Artigo]
The sesquiterpenes cadina-4,10(15)-dien-3-one (1) and aromadendr-1(10)-en-9-one (squamulosone) (14) along with the triterpenoid methyl ursolate (21) were incubated with the fungus Mucor plumbeus ATCC 4740. Substrates 1, ...
Flavonoids from Chiococca braquiata (Rubiaceae)
(Journal of the Brazilian Chemical Society, 2004-07-01) [Artigo]
A new flavonol 4′-methoxykaempferol-7-(acetyloxy)-3,5-O-α-L- rhamnoside (1), was isolated from the leaves of Chiococca braquiata, along with three known flavonoids apigenin, 7-O-methoxyquercetrin and quercetrin and four ...
Produtos naturais como candidatos a fármacos úteis no tratamento do mal de Alzheimer
(Química Nova, 2004-07-01) [Trabalho apresentado em evento]
Alzheimer's disease (AD) is a progressive neurodegenerative pathology with severe economic and social impact. There is currently no cure, although cholinesterase inhibitors provide effective temporary relief of symptoms ...
Natural chromenes and chromene derivatives as potential anti-trypanosomal agents
(Biological and Pharmaceutical Bulletin, 2008-03-01) [Artigo]
The aim of the study was to investigate the anti-trypanocidal activities of natural chromene and chromene derivatives. Five chromenes were isolated from Piper gaudichaudianum and P. aduncum, and a further seven derivatives ...
Rapid spot test analysis for the detection of dipyrone in pharmaceutical preparations
(Analytical Sciences, 2000-03-01) [Artigo]