Now showing items 1-3 of 3
Molecular hybridization: A useful tool in the design of new drug prototypes
(Current Medicinal Chemistry, 2007-07-01) [Resenha]
Molecular hybridization is a new concept in drug design and development based on the combination of pharmacophoric moieties of different bioactive substances to produce a new hyrid compound with improved affinity and ...
New anti-Alzheimer drugs from biodiversity: the role of the natural acetylcholinesterase inhibitors
(Mini-Reviews in Medicinal Chemistry, 2005-10-01) [Resenha]
Alzheimer's disease (AD) is a progressive neurodegenerative pathology with severe economic and social impact. There is currently no cure, although cholinesterase inhibitors provide effective temporary relief of symptoms ...
Patents of drugs extracted from Brazilian medicinal plants
(Expert Opinion on Therapeutic Patents, 2009-04-01) [Resenha]
Background: Plants synthesise a vast repertoire of chemicals with various biological activities. Brazilian enormous botanical diversity facilitates the development of novel ethical drugs for the treatment of diseases in ...