Now showing items 1-10 of 19
Immunostimulatory effects of the phenolic compounds from lichens on nitric oxide and hydrogen peroxide production
(Brazilian Journal of Pharmacognosy, 2009-10-01) [Artigo]
The effects of isolated compounds from Brazilian lichens and their derivatives on H 2O 2 and NO production were studied using murine macrophages as a part of an attempt to understand their possible immunomodulatory properties. ...
Atividade anti-micobacteriana de extratos de folhas de Byrsonima crassa Nied
(Revista Brasileira de Plantas Medicinais, 2008-12-01) [Artigo]
In this study, the antimycobacterial activity of chloroformic and methanolic extracts obtained from Byrsonima crassa leaves was evaluated. Antimycobacterial activity was assessed through the microtechnique named Microplate ...
Byrsonima crassa Niedenzu (IK): Antimicrobial activity and chemical study
(Revista de Ciências Farmacêuticas Básica e Aplicada, 2005-12-01) [Artigo]
The methanolic extract of leaves from Byrsonima crassa, a Brazilian medicinal plant, was analyzed by CC and HPLC. Four constituents were isolated and identified as quercetin, methyl gallate, (-)-epigallocatechin gallate ...
Comparative study of disk diffusion and microdilution methods for evaluation of antifungal activity of natural compounds against medical yeasts Candida spp and Cryptococcus sp
(Revista de Ciências Farmacêuticas Básica e Aplicada, 2007-12-01) [Artigo]
Antifungal activity of natural products has been tested by adapting methods designed for synthetic drugs. In this study, two methods for the determination of antifungal activity of natural products, agar diffusion and broth ...
Avaliação da atividade mutagênica do resíduo sólido de uma fábrica de confecções de meias e lingerie em ensaios com Salmonella typhimurium
(Revista de Ciencias Farmaceuticas, 2003-12-01) [Artigo]
Cancer is one of the most hazardous effects to human health caused by the exposition to chemical agents. The search for new technological solutions in the industrial field led to a rapid increase in the productive sector, ...
Flavonóides de Calotropis procera R. Br. (Asclepiadaceae)
(Revista Brasileira de Plantas Medicinais, 2008-02-01) [Artigo]
In this work we report the identification of two flavonol glycosides isolated from the leaves of Calotropis procera R. Br. (Asclepiadaceae), a plant species with large occurrence in Northwest of Brazil with some applications ...
Glifosato: Propriedades, toxicidade, usos e legislação
(Química Nova, 2002-07-01) [Artigo]
This paper supplies a compact revision on the herbicide glyphosate physic-chemistry characteristic mains, including toxicity and valid Brazilian legislation for its use.
Myeloperoxidase inhibitory and radical scavenging activities of flavones from Pterogyne nitens
(Chemical and Pharmaceutical Bulletin, 2008-05-19) [Artigo]
Two new flavone glucosides, nitensosides A and B (1, 2), together with four known compounds, sorbifolin (3), sorbifolin 6-O-β-glucopyranoside (4), pedalitin (5), and pedalitin 6-O-β-glucopyranoside (6) were isolated from ...
Molecular hybridization: A useful tool in the design of new drug prototypes
(Current Medicinal Chemistry, 2007-07-01) [Resenha]
Molecular hybridization is a new concept in drug design and development based on the combination of pharmacophoric moieties of different bioactive substances to produce a new hyrid compound with improved affinity and ...
nor-Lignans from the leaves of Styrax ferrugineus (Styracaceae) with antibacterial and antifungal activity
(Phytochemistry, 2000-11-30) [Artigo]
Chemical examination of the leaves of Styrax ferrugineus yielded 5-[3'-(β-D-glucopyranosyloxy)propyl]-7-methoxy-2-(3',4'-dime-thoxyphenyl) benzofuran, along with the known nor-lignans 5-(3'-hydroxypropyl)-7-methoxy-2-(3' ...