Now showing items 1-6 of 6
Myeloperoxidase inhibitory and radical scavenging activities of flavones from Pterogyne nitens
(Chemical and Pharmaceutical Bulletin, 2008-05-19) [Artigo]
Two new flavone glucosides, nitensosides A and B (1, 2), together with four known compounds, sorbifolin (3), sorbifolin 6-O-β-glucopyranoside (4), pedalitin (5), and pedalitin 6-O-β-glucopyranoside (6) were isolated from ...
Molecular hybridization: A useful tool in the design of new drug prototypes
(Current Medicinal Chemistry, 2007-07-01) [Resenha]
Molecular hybridization is a new concept in drug design and development based on the combination of pharmacophoric moieties of different bioactive substances to produce a new hyrid compound with improved affinity and ...
Natural chromenes and chromene derivatives as potential anti-trypanosomal agents
(Biological and Pharmaceutical Bulletin, 2008-03-01) [Artigo]
The aim of the study was to investigate the anti-trypanocidal activities of natural chromene and chromene derivatives. Five chromenes were isolated from Piper gaudichaudianum and P. aduncum, and a further seven derivatives ...
HPLC-EICD: An Useful Tool for the Pursuit of Novel Analytical Strategies for the Detection of Antioxidant Secondary Metabolites
(Journal of the Brazilian Chemical Society, 2003-11-24) [Artigo]
Living cells are continuously exposed to a variety of challenges that exert oxidative stress and are directly related with senescence and the onset of various pathological conditions such as coronary heart disease, rheumatoid ...
Comparative study of disk diffusion and microdilution methods for evaluation of antifungal activity of natural compounds against medical yeasts Candida spp and Cryptococcus sp
(Revista de Ciências Farmacêuticas Básica e Aplicada, 2007-12-01) [Artigo]
Antifungal activity of natural products has been tested by adapting methods designed for synthetic drugs. In this study, two methods for the determination of antifungal activity of natural products, agar diffusion and broth ...
nor-Lignans from the leaves of Styrax ferrugineus (Styracaceae) with antibacterial and antifungal activity
(Phytochemistry, 2000-11-30) [Artigo]
Chemical examination of the leaves of Styrax ferrugineus yielded 5-[3'-(β-D-glucopyranosyloxy)propyl]-7-methoxy-2-(3',4'-dime-thoxyphenyl) benzofuran, along with the known nor-lignans 5-(3'-hydroxypropyl)-7-methoxy-2-(3' ...