THE ASSESSMENT OF ZINC STATUS BY THE ZINC TOLERANCE-TEST IN THYROID-DISEASE
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Data
1992-01-01
Autores
Pimenta, W. P.
Brandaoneto, J.
Curi, P. R.
Título da Revista
ISSN da Revista
Título de Volume
Editor
Dustri-verlag Dr Karl Feistle
Resumo
Zinc status was evaluated in 12 hyperthyroid and in 7 hypothyroid patients in comparison with 8 euthyroid individuals by the oral zinc tolerance test and by the determination of urinary zinc excretion. Hyperthyroid patients presented a basal serum concentration similar to that of euthyroid individuals but greater urinary zinc excretion, indicating the occurrence of zinc depletion from tissues to the blood stream caused by the catabolism inherent in the hyperthyroid state. Hyperthyroidism also caused lower zinc assimilation by tissues after zinc ingestion. Hypothyroid individuals present lower basal zinc levels in serum than euthyroid and hyperthyroid individuals and urinary zinc excretion similar to that of euthyroid individuals. No changes in the parameters measured were observed after zinc load, suggesting reduced or delayed intestinal absorption and zinc assimilation by tissues. The present data are indicative of zinc deficiency, the lower intestinal zinc absorption probably being one of the contributing factors.
Descrição
Palavras-chave
SERUM ZINC, THYROID DISEASE, URINARY ZINC EXCRETION, ZINC LOAD
Como citar
Trace Elements In Medicine. Munchen-deisenhofen: Dustri-verlag Dr Karl Feistle, v. 9, n. 1, p. 34-37, 1992.