Droplet counter-current chromatography of indole alkaloids from Tabernaemontana hilariana

Nenhuma Miniatura disponível

Data

1999-03-01

Autores

Cardoso, CAL
Vilegas, Wagner [UNESP]

Título da Revista

ISSN da Revista

Título de Volume

Editor

Wiley-Blackwell

Resumo

This paper reports the separation of the indole alkaloids from the benzene extract of the root barks of Tabernaemontana hilariana (Apocynaceae). The crude alkaloid fraction was fractionated by droplet counter-current chromatography using a low polarity mixture (hexane:ethyl acetate:ethanol:water). Nine indole alkaloids (3-hydroxycoronaridine, coronaridine, voacangine, 3-(2-oxopropyl) coronaridine, voacangine hydroxyindolenine, ibogamine, voacangine pseudoindoxyl, coronaridine pseudoindoxyl and tabernanthine) were identified using thin laver chromatography gas chromatography coupled with mass spectrometry and nuclear magnetic resonance spectroscopy. Copyright (C) 1999 John Wiley & Sons, Ltd.

Descrição

Palavras-chave

Tabernaemontana hilariana, Apocynacene, droplet counter-current chromatography, indole alkaloids

Como citar

Phytochemical Analysis. W Sussex: John Wiley & Sons Ltd, v. 10, n. 2, p. 60-63, 1999.