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dc.contributor.authorMigliorini, R. H.
dc.contributor.authorLimaverde, J. S.
dc.contributor.authorMachado, C. R.
dc.contributor.authorCardona, GMP
dc.contributor.authorGarofalo, MAR
dc.contributor.authorKettelhut, I. C.
dc.date.accessioned2014-05-20T15:22:32Z
dc.date.available2014-05-20T15:22:32Z
dc.date.issued1992-10-01
dc.identifierhttp://ajpregu.physiology.org/content/263/4/R857
dc.identifier.citationAmerican Journal of Physiology. Bethesda: Amer Physiological Soc, v. 263, n. 4, p. R857-R862, 1992.
dc.identifier.issn0002-9513
dc.identifier.urihttp://hdl.handle.net/11449/33484
dc.description.abstractLipolytic activity of fish (Hoplias malabaricus), toad (Bufo paracnemis), and snake (Philodryas patagoniensis) adipose tissue was investigated in vivo and in vitro. Catecholamines or glucagon did not affect the release of free fatty acids (FFA) by incubated fish and toad adipose tissue. Catecholamines also failed to activate snake adipose tissue lipolysis, which even decreased in the presence of epinephrine. However, glucagon stimulated both the lipolytic activity of reptilian tissue in vitro and the mobilization of FFA to plasma when administered to snakes in vivo. The release of FFA from incubated fish, amphibian, and reptilian adipose tissue increased markedly in the presence of cAMP or xanthine derivatives, inhibitors of phosphodiesterase. Forskolin or fluoride, activators of specific components of the adenylate cyclase system, strongly stimulated toad adipose tissue lipolysis. The data suggest that adipocyte triacylglycerol lipase of ectotherm vertebrates is activated by a cAMP-mediated phosphorylation and that the organization of the membrane-bound adenylate cyclase system is similar to that of mammals.en
dc.format.extentR857-R862
dc.language.isoeng
dc.publisherAmer Physiological Soc
dc.relation.ispartofAmerican Journal of Physiology
dc.sourceWeb of Science
dc.subjectFISHpt
dc.subjectToadpt
dc.subjectSNAKEpt
dc.subjectFREE FATTY ACIDSpt
dc.subjectGLYCEROLpt
dc.subjectCAMPpt
dc.subjectXANTHINE DERIVATIVESpt
dc.subjectFORSKOLINpt
dc.subjectF-pt
dc.subjectCatecholaminespt
dc.subjectGLUCAGONpt
dc.titleCONTROL OF ADIPOSE-TISSUE LIPOLYSIS IN ECTOTHERM VERTEBRATESen
dc.typeArtigo
dcterms.licensehttp://www.the-aps.org/mm/Publications/Info-For-Authors/Copyright
dcterms.rightsHolderAmer Physiological Soc
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.description.affiliationSTATE UNIV SAO PAULO,SCH VET MED,DEPT MORPHOL & PHYSIOL,BR-14870 JABOTICABAL,SP,BRAZIL
dc.description.affiliationUNIV SAO PAULO,SCH MED,DEPT PHYSIOL,BR-14049 RIBEIRAO PRETO,SP,BRAZIL
dc.description.affiliationUnespSTATE UNIV SAO PAULO,SCH VET MED,DEPT MORPHOL & PHYSIOL,BR-14870 JABOTICABAL,SP,BRAZIL
dc.identifier.wosWOS:A1992JU80600065
dc.rights.accessRightsAcesso restrito
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Ciências Agrárias e Veterinárias, Jaboticabalpt
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