Fluoride dose response in pH-cycling models using bovine enamel
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Data
2005-01-01
Autores
Vieira, AED
Delbem, ACB
Sassaki, K. T.
Rodrigues, E.
Cury, J. A.
Cunha, Robson Frederico [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Karger
Resumo
The aim of this study was to establish methodologies for verification of the fluoride solution dose-response relationship using bovine enamel and pH-cycling models. Six models of the cariogenic challenge were performed, varying the time of demineralization and pH, time of remineralization, composition of de- and remineralization solutions, frequency and time of application of treatment solutions and pH-cycling duration. For the evaluation of the fluoride effect on caries dynamics, two proposed models provided for improvement in standardization of methods leading to a higher level of precision, demonstrating a dose response between treatments with regard to surface microhardness and Delta Z. For the evaluation of the fluoride effect on enamel remineralization, the addition of fluoride to the de- and remineralization solutions and the reduction of frequency and time of application of fluoride solutions led to a more suitable pH-cycling model. Copyright (C) 2005 S. Karger AG, Basel.
Descrição
Palavras-chave
fluoride effect on caries dynamics, fluoride effect on enamel remineralization, microhardness analysis, in vitro pH-cycling models, bovine enamel, topical fluoride, fluoride solution dose-response relationship
Como citar
Caries Research. Basel: Karger, v. 39, n. 6, p. 514-520, 2005.