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dc.contributor.authorDeCaro, G.
dc.contributor.authorPolidori, C.
dc.contributor.authorMenani, José Vanderlei [UNESP]
dc.contributor.authorJohnson, A. K.
dc.date.accessioned2014-05-20T15:26:44Z
dc.date.available2014-05-20T15:26:44Z
dc.date.issued1997-12-31
dc.identifierhttp://dx.doi.org/10.1016/S0031-9384(97)00380-6
dc.identifier.citationPhysiology & Behavior. Oxford: Pergamon-Elsevier B.V., v. 63, n. 1, p. 15-23, 1997.
dc.identifier.issn0031-9384
dc.identifier.urihttp://hdl.handle.net/11449/36827
dc.description.abstractBombesin (BN) elicits in the rat important behavioural modifications, including inhibition of food and of water intake. Recently, it has been observed that the peptide also inhibits the intake of sodium chloride. To stare whether BN possesses a selective antinatriorexic effect or it elicits only an aspecific depression of ingestive behaviour, we studied the effects of this peptide on the intake of sodium, water or sucrose of Wistar rats after injections into the fourth brain ventricle or into selected brain areas involved in the control of sodium intake, containing BN-like peptides and/or their precursors or specific receptors. We observed that: a) BN (100-200 ng/rat) injected into the fourth brain ventricle inhibits not only the intake of 2% NaCl of sodium depleted rats but also that of water and of 5% sucrose; b) BN (5-50 ng/rat) administered into the nucleus of the solitary tract and the medial amygdala does not influence the intake of these fluids and c) BN (5-50 ng/rat) injected into the paraventricular nucleus does not influence the intake of water and 5% sucrose but potently inhibits that of 2% NaCl. We concluded that the inhibitory effect elicited on salt intake by intracranial administration of BN is selective for this behaviour and is not the expression of an aspecific depression of ingestive behaviour. (C) 1998 Elsevier B.V.en
dc.format.extent15-23
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.ispartofPhysiology & Behavior
dc.sourceWeb of Science
dc.subjectbombesinpt
dc.subjectsodium appetitept
dc.subjectnucleus of the solitary tractpt
dc.subjectmedial amygdalapt
dc.subjectparaventricular nucleuspt
dc.titleBombesin affects the central nervous system to produce sodium intake inhibition in ratsen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dcterms.rightsHolderElsevier B.V.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUNIV IOWA
dc.description.affiliationPAULISTA STATE UNIV,SCH DENT,DEPT PHYSIOL,BR-14801903 ARARAQUARA,SP,BRAZIL
dc.description.affiliationUNIV IOWA,DEPT PSYCHOL,IOWA CITY,IA 52242
dc.description.affiliationUnespPAULISTA STATE UNIV,SCH DENT,DEPT PHYSIOL,BR-14801903 ARARAQUARA,SP,BRAZIL
dc.identifier.doi10.1016/S0031-9384(97)00380-6
dc.identifier.wosWOS:A1997YG52700003
dc.rights.accessRightsAcesso restrito
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araraquarapt
dc.identifier.lattes1023597870118105
unesp.author.lattes1023597870118105
unesp.author.orcid0000-0003-1167-4441[3]
dc.relation.ispartofjcr2.517
dc.relation.ispartofsjr1,088
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