Plasmodium vivax infection among Duffy antigen-negative individuals from the Brazilian Amazon region: an exception?
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Data
2007-10-01
Autores
Cavasini, Carlos Eugenio
de Mattos, Luiz Carlos
D'Almeida Couto, Alvaro Augusto
Bonini-Omingos, Claudia Regina
Valencia, Socrates Herrera
de Souza Neiras, Wanessa Christina
Alves, Renata Tome
Baptista Rossit, Andrea Regina
Castilho, Lilian
Dantas Machado, Ricardo Luiz
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Editor
Elsevier B.V.
Resumo
We present evidence for Plasmodium vivax infection among Duffy blood group-negative inhabitants of Brazil. The P. vivax identification was determined by both genotypic and non-genotypic screening tests. The Duffy blood group was genotyped by PCR/RFLP and phenotyped using a microtyping kit. We detected two homozygous FY*B-33 carriers infected by P vivax, whose circumsporozoite protein genotypes were VK210 and/or P. vivax-like. Additional efforts are necessary in order to clarify the evidence that P. vivax is being transmitted among Duffy blood group-negative patients from the Brazilian Amazon region. (C) 2007 Published by Elsevier Ltd on behalf of Royal Society of Tropical Medicine and Hygiene.
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Palavras-chave
vivax malaria, Plasmodium vivax, Duffy blood group, Duffy antigen binding, protein, protozoan proteins, Brasil
Como citar
Transactions of the Royal Society of Tropical Medicine and Hygiene. New York: Elsevier B.V., v. 101, n. 10, p. 1042-1044, 2007.