SINUS HISTIOCYTOSIS WITH MASSIVE LYMPHADENOPATHY (ROSAI-DORFMAN DISEASE) - CYTOMORPHOLOGIC ANALYSIS ON FINE-NEEDLE ASPIRATES

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Data

1992-01-01

Autores

Schmitt, F. C.

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Editor

Wiley-Blackwell

Resumo

Cytomorphologic characteristics of smears from fine-needle aspirates (FNA) of three cases of sinus histiocytosis with massive lymphadenopathy (SHML) (Rosai-Dorfman disease) are described. All aspirates showed mature lymphocytes, plasma cells, and large pale histiocytes with well-preserved lymphocytes within the cytoplasm (lymphocytophagocytosis). The cases were confirmed by surgical biopsy, and the immunohistochemical findings suggested a macrophage origin for this lesion. The value of FNA analysis as an aid to diagnosis of SHML is discussed.

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Palavras-chave

SHML, LYMPH NODE DISEASE, FINE-NEEDLE ASPIRATION

Como citar

Diagnostic Cytopathology. New York: Wiley-liss, v. 8, n. 6, p. 596-599, 1992.