Solitary fibrous tumor with atypical histological features occurring in the palatine tonsil: an uncommon neoplasm in an uncommon site
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Data
2006-11-01
Autores
Macarenco, Ricardo Silvestre
Bacchi, Carlos E.
Domingues, Maria Aparecida Custódio [UNESP]
Título da Revista
ISSN da Revista
Título de Volume
Editor
Blackwell Publishing
Resumo
Solitary fibrous tumor (SFT) is an uncommon mesenchymal neoplasm that usually arises in the pleura. Although this tumor has been described in other sites, including the head and neck area, in the oropharynx it is extremely rare. We report the first case of a SFT arising from the palatine tonsil of a 62-year-old man. The tumor consisted of spindle-shaped cells distributed in a haphazard pattern and presented atypical histological features such as hypercellular areas and high mitotic count. Immunohistochemical studies showed strong positivity for CD34 and bcl-2, and weak positivity for desmin. Smooth muscle actin, S-100 protein and cytokeratines were negative. The patient was well without disease 1 year after surgery.
Descrição
Palavras-chave
oropharynx, palatine tonsil, solitary fibrous tumor
Como citar
Journal of Oral Pathology & Medicine. Oxford: Blackwell Publishing, v. 35, n. 10, p. 602-605, 2006.