Now showing items 1-3 of 3
Structure, function and evolution of the animal mitochondrial replicative DNA helicase
(Critical Reviews In Biochemistry And Molecular Biology, 2016-01-02) [Resenha]
The mitochondrial replicative DNA helicase is essential for animal mitochondrial DNA (mtDNA) maintenance. Deleterious mutations in the gene that encodes it cause mitochondrial dysfunction manifested in developmental delays, ...
Alternative respiratory chain enzymes: Therapeutic potential and possible pitfalls
(Biochimica Et Biophysica Acta-molecular Basis Of Disease, 2019-04-01) [Resenha]
The alternative respiratory chain (aRC), comprising the alternative NADH dehydrogenases (NDX) and quinone oxidases (AOX), is found in microbes, fungi and plants, where it buffers stresses arising from restrictions on ...
Xenotopic expression of alternative electron transport enzymes in animal mitochondria and their impact in health and disease
(Cell Biology International, 2018-06-01) [Resenha]
The mitochondrial respiratory chain in vertebrates and arthropods is different from that of most other eukaryotes because they lack alternative enzymes that provide electron transfer pathways additional to the oxidative ...