Iridoids from the aerial parts of Verbena littoralis (Verbenaceae)
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Data
2004-08-01
Autores
Castro-Gamboa, I
Castro, O.
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Título de Volume
Editor
Elsevier B.V.
Resumo
The iridoids, 6S-hydroxy-8S-methyl-4-methylene-hexahydro-cyclopenta[c]pyran-3-one and 6S,9S-dihydroxy-8S-methyl-4methylene-hexahydro-cyclopenta[c]pyran-3-one, were isolated from the aerial parts of Verbena littoralis. Their structures and stereochemistry were elucidated by means of NMR spectral data analysis. Both compounds showed moderate in vitro activity against gram positive and negative bacteria as well as moderate in vivo intestinal peristaltic action in mouse. The iridoids also showed moderate free radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) as well as antioxidant activity, the latter being evidenced by redox properties measured using EICD-HPLC. (C) 2004 Elsevier Ltd. All rights reserved.
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Palavras-chave
Verbena littoralis, Verbenaceae, iridoids, antibacterial activity, antioxidant
Como citar
Phytochemistry. Oxford: Pergamon-Elsevier B.V., v. 65, n. 16, p. 2369-2372, 2004.