Effect of Amblyomma cajennense Ticks on the Immune Response of BALB/c Mice and Horses
Nenhuma Miniatura disponível
Data
2008-01-01
Autores
Castagnolli, Karina Carrao [UNESP]
Ferreira, Beatriz Rossetti
Franzin, Alessandra Mara
de Castro, Marcio Botelho
Juan Szabo, Matias Pablo
Título da Revista
ISSN da Revista
Título de Volume
Editor
Blackwell Publishing
Resumo
This work evaluated the effect of the Amblyomma cajennense tick on the immune response of BALB/c mice and on horse lymph node cell proliferation. We observed that mice do not develop resistance to nymphs of this tick species and that lymphocyte proliferation of this host is inhibited by tick saliva, nymphal extract, or infestations. Horse lymph node cell proliferation is inhibited by tick saliva as well. Mice lymphocytes under the effect of tick saliva, nymphal extract, or infestations display a predominantly. p Th-2 cytokine production pattern. Observed results partially explain this tick's disease vectoring capacity and broad host range.
Descrição
Palavras-chave
Amblyomma cajennense, immune response, horse, BALB/c mice
Como citar
Animal Biodiversity and Emerging Diseases: Prediction and Prevention. Oxford: Blackwell Publishing, v. 1149, p. 230-234, 2008.