ACAO ANTIARRITMICA DA METOCLOPRAMIDA (PLASIL®) EM INTOXICACAO DIGITALICA EXPERIMENTAL. COMPARACAO COM A DIFENIL-HIDANTOINA

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Data

1982-12-01

Autores

Bastos Ramos, W. P.
Minossi, José Guilherme [UNESP]
Silva, C. J.

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Resumo

The antiarrhythmic action of metoclopramide in cardiac arrhythmias caused by toxic doses of desacetyl-lanatoside C and digitoxin was studied in dogs. A comparison was made between the efficacy of metoclopramide and diphenylhydantoin in arrhythmias caused by digitoxin. The results indicate that metoclopramide antagonized the arrhythmias induced by desacetyl-lanatoside C, while causing a transitory reversion of those induced by digitoxin in most of the experiments. Diphenylhydantoin failed to show an arrhythmic effect in the majority of the tested animals.

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Palavras-chave

antiarrhythmic agent, deslanoside, digitoxin, lanatoside c, metoclopramide, phenytoin, lanatoside, clinical article, drug comparison, drug intoxication, drug therapy, heart, heart arrhythmia, human, intoxication, therapy, animal, comparative study, dog, electrocardiography, iatrogenic disease, Animal, Arrhythmia, Comparative Study, Deslanoside, Digitoxin, Dogs, Electrocardiography, English Abstract, Lanatosides, Metoclopramide, Phenytoin

Como citar

Revista Paulista de Medicina, v. 100, n. 2, p. 8-10, 1982.