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SPERM QUALITY IN ADULT MALE RATS EXPOSED TO CADMIUM IN UTERO and LACTATION
(Journal of Toxicology and Environmental Health: Part A Current Issues, 2012-01-01) [Artigo]
Recent studies indicate that several anomalies of the male reproductive system may be produced by acute or chronic exposure to chemical substances released into the environment, attributed to increased industrial development. ...
The sympathetic adrenomedullary system, but not the hypothalamic-pituitary-adrenal axis, participates in aorta adaptive response to stress: nitric oxide involvement
(Autonomic Neuroscience-basic & Clinical, 2000-10-02) [Artigo]
Stress induced a decrease in the reactivity of the aorta to noradrenaline (NA), as a consequence of an endothelial nitric oxide (NO) system hyperactivity. The main characteristic of the stress response is activation of the ...
Fenvalerate, A Pyrethroid Insecticide, Adversely Affects Sperm Production and Storage in Male Rats
(Journal of Toxicology and Environmental Health: Part A Current Issues, 2008-01-01) [Artigo]
The aim of this study was to investigate the potential estrogenic activity of fenvalerate by examining reproductive and fertility capabilities in Wistar rats. Adult male animals were treated for 30 d with 20 or 40 mg/kg/d ...
Early Changes Induced by Short-Term Low-Dose Cadmium Exposure in Rat Ventral and Dorsolateral Prostates
(Microscopy Research and Technique, 2011-11-01) [Artigo]
Prostate cancer (PCa) is the most commonly diagnosed cancer in men. The etiology of PCa in humans is multifactorial and includes age, ethnicity, environmental factors, and other unknown causes. Epidemiological and experimental ...
Caffeine reduces cadmium accumulation in the organism and enhances the levels of antioxidant protein expression in the epididymis
(Reproductive Toxicology, 2013-01-01) [Artigo]
The aim of this study was to investigate the effects of caffeine (20. mg/L) intake on cadmium (15. mg/L) accumulation in the rat blood, testes, epididymis and prostate as well as cadmium-induced changes to the antioxidant ...
Reproductive effects in male rats exposed to diuron
(Reproductive Toxicology, 2007-01-01) [Artigo]
Diuron is a ureic herbicide considered to have very low toxicity. The present study evaluated several aspects of reproductive toxicity of diuron in adult male rats. Diuron was diluted in corn oil and administered by oral ...
Effect of alkalinisation on the kinetic of the organophosphate insecticide by the kidney of dogs
(Toxicology, 2001-07-08) [Resumo]
Antioxidant defense in rat brain regions after developmental lead exposure
(Toxicology, 2001-12-14) [Artigo]
Oxidative stress is considered a possible molecular mechanism involved in Pb neurotoxicity. Considering the vulnerability of the developing brain to Pb neurotoxicity, this study was carried out to investigate the effects ...
Metalloproteinase inhibition protects against reductions in circulating adrenomedullin during lead-induced acute hypertension
(Basic & Clinical Pharmacology & Toxicology, 2015-06-01) [Artigo]
Intoxication with lead (Pb) results in increased blood pressure by mechanisms involving matrix metalloproteinases (MMPs). Recent findings have revealed that MMP type two (MMP-2) seems to cleave vasoactive peptides. This ...
Correlations among antiangiogenic factors and trace elements in hypertensive disorders of pregnancy
(Journal Of Trace Elements In Medicine And Biology, 2015-01-01) [Artigo]
Although a number of studies have measured circulating levels of some trace elements in preeclampsia (PE) and compared to healthy pregnant (HP), there is no consensus yet about the deficiency of some metals and development ...