RSS 1.0Departamento de Ciências Biológicas
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Proposta de um protocolo de terapia celular para o tratamento da doença pulmonar obstrutiva crônica
Ribeiro-Paes, J. T.
; ; ; ; ; (Revista Portuguesa de Pneumologia, 2014) [Artigo]
The main feature of pulmonary emphysema is airflow obstruction resulting from the destruction of the alveolar walls distal to the terminal bronchioles. Existing clinical approaches have improved and extended the quality ... -
Natural rubber latex biodevice as controlled release system for chronic wounds healing
De Barros, Natan Roberto; Heredia-Vieira, Silvia Cristina ; Borges, Felipe Azevedo ; Benites, Nikollas Moreira ; Dos Reis, Camila Eugênia ; Miranda, Matheus Carlos Romeiro ; ; Herculano, Rondinelli Donizetti (Biomedical Physics and Engineering Express, 2018) [Artigo]
The chronic wounds problem affect millions of people worldwide, becoming a great challenge to the healthcare systems. The normal healing consists of three phases: Inflammation, proliferation and remodelation. Problems in ... -
Number of oocytes retrieved per donor during OPU and its relationship with in vitro embryo production and field fertility following embryo transfer
; ; ; ; ; ; ; ; Nogueira, Marcelo Fábio Gouveia; et al. (Animal Reproduction, 2017) [Artigo]
The association of OPU-IVEP is an important instrument to drive genetic progress. In vitro embryo production (IVEP) has remarkably expanded in the last decade compared to in vivo embryo production. Because of the high ... -
Supplementing in vitro embryo production media by NPPC and sildenafil affect the cytoplasmic lipid content and gene expression of bovine cumulus-oocyte complexes and embryos
Botigelli, Ramon Cesar; Razza, Eduardo Montanari ; Pioltine, Elisa Mariano ; Fontes, Patricia Kubo ; ; ; Nogueira, Marcelo Fábio Gouveia (Reproductive Biology, 2018) [Artigo]
In our study, we added natriuretic peptide type C (NPPC) and/or sildenafil during in vitro maturation (IVM) of bovine cumulus-oocyte complexes (COCs) followed by in vitro culture (IVC) of embryos with or without sildenafil. ... -
Analysis of antioxidant, cytotoxic and mutagenic potential of Agave sisalana Perrine extracts using Vero cells, human lymphocytes and mice polychromatic erythrocytes
; dos Santos, Maristela Oliveira; Barbon, Fabiane Faria ; Manjerona, Bruna Aparecida ; Meirelles, Bruno Rosa ; de Oliva Neto, Pedro ; ; dos Santos, Lucinéia ; Camargo, Isabel Cristina Cherici ; de Souza, Edislane Barreiros (Biomedicine and Pharmacotherapy, 2018) [Artigo]
Brazilian Northeast is the world's largest producer of Agave sisalana Perrine for the supply of the sisal fiber. About 95% of plant biomass, which comprise the mucilage and sisal juice, is considered a waste residual is ... -
Data Descriptor: Automatized image processing of bovine blastocysts produced in vitro for quantitative variable determination
Rocha, José Celso; Passalia, Felipe José ; ; Takahashi, Maria Beatriz ; ; ; ; ; ; Nogueira, Marcelo Fábio Gouveia (Scientific Data, 2017) [Artigo]
There is currently no objective, real-time and non-invasive method for evaluating the quality of mammalian embryos. In this study, we processed images of in vitro produced bovine blastocysts to obtain a deeper comprehension ... -
Handling culture medium composition for optimizing plant cell suspension culture in shake flasks
Fidemann, Tiago; de Araujo Pereira, Gabriela Aparecida ; Heluy, Tárik Reis ; Gallego, Rodrigo Boccoli ; Bertão, Mônica Rosa ; da Silva, Regildo Márcio Gonçalves ; (Plant Cell, Tissue and Organ Culture, 2018) [Artigo]
This work aimed to optimize statistically the culture medium composition for cell plant suspension culture using as a model Capsicum baccatum L. var. pendulum cells. The cell growth was maximized as well as the secondary ... -
Ketoprofen Loaded in Natural Rubber Latex Transdermal Patch for Tendinitis Treatment
Floriano, Juliana Ferreira; de Barros, Natan Roberto ; Cinman, José Luiz Ferreira ; da Silva, Rosangela Gonçalves ; Loffredo, Augusto Villela ; Borges, Felipe Azevedo ; ; ; Garms, Bruna Cambraia ; de Oliveira Graeff, Carlos Frederico et al. (Journal of Polymers and the Environment, 2018) [Artigo]
Ketoprofen is an analgesic with potent anti-inflammatory activity against acute inflammation, subacute inflammation, for the acute and long-term treatment of various inflammatory pathologies, as rheumatoid arthritis and ... -
Holistic protocol for callus culture optimization using statistical modelling
Fidemann, Tiago; de Araujo Pereira, Gabriela Aparecida ; Bossard Nascimento, Lia ; Moraes, Milena Cristina ; Bertão, Mônica Rosa ; da Silva, Regildo Márcio Gonçalves ; (Natural Product Research, 2018) [Artigo]
Plants endue a key role against illnesses caused by oxidative stress. These attributes are frequently associated with polyphenolic compounds. However, presence and concentration of secondary metabolites are affected by ... -
A Method Based on Artificial Intelligence To Fully Automatize The Evaluation of Bovine Blastocyst Images
Rocha, José Celso; Passalia, Felipe José ; ; Takahashi, Maria Beatriz ; Ciniciato, Diego De Souza ; ; ; ; ; et al. (Scientific Reports, 2017) [Artigo]
Morphological analysis is the standard method of assessing embryo quality; however, its inherent subjectivity tends to generate discrepancies among evaluators. Using genetic algorithms and artificial neural networks (ANNs), ... -
Physical, chemical and antimicrobial implications of the association of propolis with a natural rubber latex membrane
Zancanela, Daniela Cervelle; Herculano, Rondinelli Donizetti ; Funari, Cristiano Soleo ; Marcos, Caroline Maria ; Almeida, Ana Marisa Fusco ; Guastaldi, Antônio Carlos (Materials Letters, 2017) [Artigo]
Natural rubber latex (NRL) has shown interesting biomedical properties, such as wound healing improvement, tissue regeneration stimulation and angiogenesis. Propolis, produced by honey bees, acts as an antiseptic agent in ... -
Interaction between estradiol and 5-HT1A receptors in the median raphe nucleus on acquisition of aversive information and association to the context in ovariectomized rats
Andrade, Telma Gonçalves Carneiro Spera de; Silva, João Victor dos Santos ; Batistela, Matheus Fitipaldi ; Frei, Fernando ; Sant'Ana, Ana Beatriz (Neurobiology of Stress, 2017) [Artigo]
The median raphe nucleus (MRN) is related to stress resistance and defensive responses, a crucial source of serotonergic neurons that project to prosencephalic structures related to stress and anxiety. Estrogen receptors ... -
Microencapsulation of an anthocyanin-rich blackberry (Rubus spp.) by-product extract by freeze-drying
Yamashita, Camila; ; dos Santos, Catarina ; Mayer, Cassia Roberta Malacrida ; ; Branco, Ivanise Guilherme (LWT - Food Science and Technology, 2017) [Artigo]
One approach to improving sustainable food production is to add value to fruit by-products, which are currently used as animal feed or discarded, yet may be useful sources of natural antioxidants due to their phenolic ... -
UV/Vis spectroscopy combined with chemometrics for monitoring solid-state fermentation with Rhizopus microsporus var. oligosporus
Ito, Shuri; Barchi, Augusto César ; Escaramboni, Bruna ; de Oliva Neto, Pedro ; Herculano, Rondinelli Donizetti ; Azevedo Borges, Felipe ; Romeiro Miranda, Matheus Carlos ; Fernández Núñez, Eutimio Gustavo (Journal of Chemical Technology and Biotechnology, 2017) [Artigo]
BACKGROUND: Difficulties in bioprocess monitoring are a drawback of solid-state fermentation (SSF). Specifically, monitoring of enzyme activities in SSF is not an easy task. This work aimed to calibrate partial least squares ... -
Melatonin reduces angiogenesis in serous papillary ovarian carcinoma of ethanol-preferring rats
Zonta, Yohan Ricci; ; Camargo, Isabel Cristina C. ; Domeniconi, Raquel F. ; Lupi Júnior, Luiz Antonio ; Pinheiro, Patricia Fernanda F. ; ; Martinez, Francisco Eduardo ; Chuffa, Luiz Gustavo A. (International Journal of Molecular Sciences, 2017) [Artigo]
Angiogenesis is a hallmark of ovarian cancer (OC); the ingrowth of blood vessels promotes rapid cell growth and the associated metastasis. Melatonin is a well-characterized indoleamine that possesses important anti-angiogenic ... -
Modeling the species richness and abundance of lotic macroalgae based on habitat characteristics by artificial neural networks: a potentially useful tool for stream biomonitoring programs
Rocha, José Celso; ; Buzzo, José Leonel L. ; de Souza, Vinícius ; Krause, Eric A. ; Bispo, Pitágoras C. ; Frei, Fernando ; Costa, Lucas S. M. ; Branco, Ciro C. Z. (Journal of Applied Phycology, 2017) [Artigo]
One of the major challenges in stream ecology is the development of computational models that can predict aspects of the community structure of organisms from these ecosystems when they are subject to natural or artificial ... -
Canopy cover as the key factor for occurrence and species richness of subtropical stream green algae (Chlorophyta)
; Tonetto, Aurélio Fajar; ; Branco, Ciro Cesar Zanini (Aquatic Botany, 2017) [Artigo]
Understanding how local and regional environmental factors influence species richness remains a key issue in ecology. Green algae (Chlorophyta) are a diverse and widely occurring group, which may be a good model for studying ... -
Novel sustained-release of stryphnodendron obovatum leaves extract using natural rubber latex as carrier
Borges, Felipe Azevedo; Siguematsu, Paula Ratsue ; Herculano, Rondinelli Donizetti ; Dos Santos, Catarina (Revista de Ciencias Farmaceuticas Basica e Aplicada, 2015) [Artigo]
Natural rubber latex biomembranes (NRL), obtained from rubber tree Hevea brasiliensis (Willd. ex A. Juss.) Mull. Arg., have been used as sustained drug release of drugs and plant extracts with medicinal properties. The ... -
A new species and records of Gripopterygidae (Plecoptera) from Rio Grande do Sul State, Southern Brazil
; Bispo, Pitágoras Da Conceição (Zootaxa, 2016) [Artigo]
Specimens of Gripopterygidae (Plecoptera) from Rio Grande do Sul State, southern Brazil were studied. A new species, Tupiperla sepeensis n. sp. is described. Tupiperla misionera Froehlich 2002 is a new record for Brazil ... -
Methods for assessing the quality of mammalian embryos: How far we are from the gold standard?
Rocha, José C.; Passalia, Felipe ; ; ; ; ; ; ; Nogueira, Marcelo Fábio Gouveia (Jornal Brasileiro de Reproducao Assistida, 2016) [Resenha]
Morphological embryo classification is of great importance for many laboratory techniques, from basic research to the ones applied to assisted reproductive technology. However, the standard classification method for both ...