PREVENCAO DE TROMBOFLEBITES PELO USO DE HEPARINA EM PACIENTES TRATADOS COM ANFOTERICINA B
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Data
1995-12-01
Autores
Lastoria, Joel Carlos [UNESP]
Marques, Silvio Alencar [UNESP]
Dillon, N. L. [UNESP]
Lastoria, S. [UNESP]
Curi, P. R. [UNESP]
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Resumo
The authors studied the incidence of thrombophlebitis in 41 patients treated intravenously with amphotericin B. The patients were divided in two different group: Group 1: patients treated with amphotericin B and hydrocortisone with heparin (1000 UI); Group 2: patients treated with amphotericin B and hydrocortisone. The results showed 23.81% of incidence of thrombophlebitis in Group 1 and 90% in Group 2. Thrombophlebitis in Group 1 ranged from mild to moderate without any change during the drug therapy. In Group 2, the incidence was 66.67% and the thrombophlebitis were severe being necessary the withdrawn of the drugs in 35.0% of the cases. We concluded that heparin, in low doses, in association with amphotericin B, was an efficient drug preventing or reducing the development of thrombophlebitis.
Descrição
Palavras-chave
amphotericin B, heparin, thrombophlebitis, amphotericin b, hydrocortisone, adolescent, adult, aged, clinical article, clinical trial, controlled clinical trial, controlled study, drug effect, female, human, incidence, male
Como citar
Medicina Cutanea Ibero-Latino-Americana, v. 23, n. 8, p. 377-382, 1995.