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dc.contributor.authorFioretto, José Roberto [UNESP]
dc.date.accessioned2014-05-27T11:18:07Z
dc.date.available2014-05-27T11:18:07Z
dc.date.issued1996-11-18
dc.identifierhttp://www.arquivosonline.com.br/pesquisartigos/Pdfs/1996/V67N3/67030002.pdf
dc.identifier.citationArquivos Brasileiros de Cardiologia, v. 67, n. 3, p. 159-164, 1996.
dc.identifier.issn0066-782X
dc.identifier.urihttp://hdl.handle.net/11449/64877
dc.description.abstractPurpose - To evaluate the influence of sustained elevations of arterial pressure on dP/dt values, which the left ventricular end diastolic pressure was kept constant. Methods - Thirteen anesthetized dogs, mechanically ventilated and submitted to thoracotomy and pharmacological autonomic block (atropine - 0.5 mg/kg IV + oxprenolol - 3 mg/kg IV) were studied. The arterial pressure elevation was obtained by mechanical constriction of the descending thoracic aorta. Analyses were made in control (C) situation and after two successives increments of arterial pressure, sustained for 10min, called hypertension 1 (H1) and hypertension 2 (H2), respectively. The end diastolic left ventricular pressure was kept constant by utilization of a perfusion system connected to the left atria. Results - Heart rate did not change (C: 125 ± 13.9bpm; H1: 125 ± 13.5bpm; H2: 123 ± 14.1bpm; p > 0.05); the LVSP increased (C: 119 ± 8.1mmHg; H1: 142 ± 7.9mmHg; H2: 166 ± 7.7mmHg; p < 0.01); the AoDP increased (C: 89 ± 11.6mmHg; H1: 99 ± 9.5mmHg; H2: 120 ± 11.8mmHg; p < 0.01); the LVEDP (C: 6.2 ± 2.48mmHg; H1: 6.3 ± 2.43mmHg; H2: 6.1 ± 2.51mmHg; p > 0.05) and the dP/dt (C: 3068 ± 1057.1mmHg/s; 3112 ± 995.7mmHg/s; H2: 3086 ± 979.5mmHg/s; p > 0.05) did not change. Conclusion - dP/dt values are not influenced by a sustained elevation of arterial pressure, when the end diastolic left ventricular pressure is kept constant.en
dc.format.extent159-164
dc.language.isopor
dc.relation.ispartofArquivos Brasileiros de Cardiologia
dc.sourceScopus
dc.subjectafterload
dc.subjectdP/dt
dc.subjectFrank-Starling mechanism
dc.subjectatropine
dc.subjectoxprenolol
dc.subjectanimal experiment
dc.subjectblood pressure
dc.subjectcontrolled study
dc.subjectheart left ventricle enddiastolic pressure
dc.subjectnonhuman
dc.subjectanimal
dc.subjectdog
dc.subjectheart contraction
dc.subjectheart left ventricle function
dc.subjectheart rate
dc.subjectphysiology
dc.subjectAnimals
dc.subjectBlood Pressure
dc.subjectDogs
dc.subjectHeart Rate
dc.subjectMyocardial Contraction
dc.subjectVentricular Function, Left
dc.titleInfluencia da elevacao sustentada da pressao arterial sobre a dP/dt do ventriculo esquerdo mantendo-se constante a pressao diastolica do ventriculo esquerdopt
dc.title.alternativeInfluence of sustained elevations of arterial pressure on the left ventricular dP/dt keeping constant the left ventricular end diastolic pressureen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/abc/paboutj.htm#03
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.description.affiliationFaculdade de Medicina de Botucat UNESP Depto de Pediatria, 18618-970 - Botucatu, SP
dc.description.affiliationUnespFaculdade de Medicina de Botucat UNESP Depto de Pediatria, 18618-970 - Botucatu, SP
dc.rights.accessRightsAcesso aberto
dc.identifier.scopus2-s2.0-0030224963
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina, Botucatupt
dc.identifier.file2-s2.0-0030224963.pdf
dc.relation.ispartofjcr1.318
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