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dc.contributor.authorMoraes-Filho, Joaquim Prado P.
dc.contributor.authorCecconello, Ivan
dc.contributor.authorGama-Rodrigues, Joaquim
dc.contributor.authorCastro, Luiz de Paula
dc.contributor.authorHenry, Maria Aparecida
dc.contributor.authorMeneghelli, Ulisses G
dc.contributor.authorQuigley, Eamonn
dc.date.accessioned2014-05-27T11:20:25Z
dc.date.available2014-05-27T11:20:25Z
dc.date.issued2002-03-02
dc.identifierhttp://dx.doi.org/10.1016/S0002-9270(01)04038-2
dc.identifier.citationAmerican Journal of Gastroenterology, v. 97, n. 2, p. 241-248, 2002.
dc.identifier.issn0002-9270
dc.identifier.urihttp://hdl.handle.net/11449/66846
dc.description.abstractThe Brazilian Consensus on Gastroesophageal Reflux Disease considers gastroesophageal reflux disease to be a chronic disorder related to the retrograde flow of gastroduodenal contents into the esophagus and/or adjacent organs, resulting in a variable spectrum of symptoms, with or without tissue damage. Considering the limitations of classifications currently in use, a new classification is proposed that combines three criteria - clinical, endoscopic, and pH-metric - providing a comprehensive and more complete characterization of the disease. The diagnosis begins with the presence of heartburn, acid regurgitation, and alarm manifestations (dysphagia, odynophagia, weight loss, GI bleeding, nausea and/or vomiting, and family history of cancer). Also, atypical esophageal, pulmonary, otorhinolaryngological, and oral symptoms may occur. Endoscopy is the first approach, particularly in patients over 40 yr of age and in those with alarm symptoms. Other exams are considered in particular cases, such as contrast radiological examination, scyntigraphy, manometry, and prolonged pH measurement. The clinical treatment encompasses behavioral modifications in lifestyle and pharmacological measures. Proton pump inhibitors in manufacturers' recommended doses are indicated, with doubling of the dose in more severe cases of esophagitis. The minimum time of administration is 6 wk. Patients who do not respond to medical treatment, including those with atypical manifestations, should be considered for surgical treatment. Of the complications of gastroesophageal reflux disease, Barrett's esophagus presents a potential development of adenocarcinoma; biopsies should be performed, independent of Barrett's esophagus extent or location. In this regard the designation short Barrett's is not important in terms of management and prognosis. © 2002 by Am. Coll. of Gastroenterology.en
dc.format.extent241-248
dc.language.isoeng
dc.relation.ispartofAmerican Journal of Gastroenterology
dc.sourceScopus
dc.subjectproton pump inhibitor
dc.subjectBarrett esophagus
dc.subjectbehavior modification
dc.subjectBrazil
dc.subjectclinical feature
dc.subjectendoscopy
dc.subjectesophagus hemorrhage
dc.subjectesophagus pressure
dc.subjectesophagus stenosis
dc.subjectgastroesophageal reflux
dc.subjecthuman
dc.subjectmanometry
dc.subjectpH measurement
dc.subjectpriority journal
dc.subjectreview
dc.subjectscintigraphy
dc.subjectulcer
dc.subjectBiopsy, Needle
dc.subjectEsophagoscopy
dc.subjectFemale
dc.subjectGastroesophageal Reflux
dc.subjectHumans
dc.subjectMale
dc.subjectPrognosis
dc.titleBrazilian consensus on gastroesophageal reflux disease: Proposals for assessment, classification, and managementen
dc.typeArtigo
dcterms.licensehttp://www.nature.com/authors/policies/license.html
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Federal de Minas Gerais (UFMG)
dc.contributor.institutionNational University of Ireland
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.description.affiliationFaculty of Medicine University of São Paulo, São Paulo
dc.description.affiliationFederal University of Minas Gerais School of Medicine, Belo Horizonte
dc.description.affiliationFaculty of Medicine State of São Paulo University, Botucatu
dc.description.affiliationFaculty of Medicine University of São Paulo, Ribeirão Preto
dc.description.affiliationNational University of Ireland, Cork
dc.description.affiliation, rua João Moura 627 conj 174, São Paulo, 05412-001
dc.identifier.doi10.1016/S0002-9270(01)04038-2
dc.rights.accessRightsAcesso restrito
dc.identifier.scopus2-s2.0-0036180921
dc.relation.ispartofjcr10.231
dc.relation.ispartofsjr4,197
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