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dc.contributor.authorDe Morales, Rogério Rizo
dc.contributor.authorMorales, Nivea de Macedo Oliveira
dc.contributor.authorRocha, Fernando Coronetti Gomes da [UNESP]
dc.contributor.authorFenelon, Sheila Bernardino
dc.contributor.authorPinto, Rogério de Melo Costa
dc.contributor.authorDa Silva, Carlos Henrique Martins
dc.date.accessioned2014-05-27T11:22:29Z
dc.date.available2014-05-27T11:22:29Z
dc.date.issued2007-06-01
dc.identifierhttp://dx.doi.org/10.1590/S0004-282X2007000300018
dc.identifier.citationArquivos de Neuro-Psiquiatria, v. 65, n. 2 B, p. 454-460, 2007.
dc.identifier.issn0004-282X
dc.identifier.issn1678-4227
dc.identifier.urihttp://hdl.handle.net/11449/69685
dc.description.abstractMultiple sclerosis (MS) is a chronic disease which may exert significant effects on the life of patients. Traditional outcome measures in MS lack in consider the effects of the disease on health-related quality of life (HRQoL). The goal of this study is to measure HRQoL in MS patients in the city of Uberlân-dia, State of Minas Gerais, Brazil. The Brazilian version of the SF-36 was applied in 23 MS patients and in 69 subjects of general population (blood donors) in Uberlândia. MS patients scored lower in all SF-36 scales than do the general population, principally in physical function domains. Patients with EDSS scores ≤3.5 had higher mean scores in four domains than do the patients with EDSS scores ≥4.0, and lower in all domains than control group. Depressive symptoms and heat intolerance showed correlation with SF-36 domains and components. In conclusion, MS patients have a significant negative impact on all HRQoL domains measured by SF-36, compared with general population, even in the stages with lower disability.en
dc.format.extent454-460
dc.language.isopor
dc.relation.ispartofArquivos de Neuro-Psiquiatria
dc.sourceScopus
dc.subjectHealth evaluation
dc.subjectMultiple sclerosis
dc.subjectQuality of life
dc.subjectadult
dc.subjectBrazil
dc.subjectclinical article
dc.subjectcontrolled study
dc.subjectcorrelation analysis
dc.subjectdepression
dc.subjectdisability
dc.subjectfemale
dc.subjectfunctional assessment
dc.subjectheat intolerance
dc.subjecthuman
dc.subjectmale
dc.subjectmultiple sclerosis
dc.subjectoutcome assessment
dc.subjectquality of life
dc.subjectrating scale
dc.subjectscoring system
dc.subjectShort Form 36
dc.subjectAdolescent
dc.subjectAdult
dc.subjectCase-Control Studies
dc.subjectCross-Sectional Studies
dc.subjectDisability Evaluation
dc.subjectFemale
dc.subjectHealth Status
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectMultiple Sclerosis
dc.subjectQuality of Life
dc.subjectQuestionnaires
dc.subjectSeverity of Illness Index
dc.subjectSickness Impact Profile
dc.titleQualidade de vida em portadores de esclerose múltiplapt
dc.title.alternativeHealth-related quality of life in multiple sclerosisen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/anp/paboutj.htm
dc.contributor.institutionUniversidade Federal de Uberlândia (UFU)
dc.contributor.institutionBCTRIMS (Comitê Brasileiro de Tratamento e Pesquisa em Esclerose Múltipla)
dc.contributor.institutionBCTRIMS
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.description.affiliationPropedêutica Neurológica Faculdade de Medicina Universidade Federal de Uberlândia, Uberlândia MG
dc.description.affiliationMédico Neurologista da UFU Médico do CETEM (Centro de Estudos Triangulino em Esclerose Múltipla) da UF BCTRIMS (Comitê Brasileiro de Tratamento e Pesquisa em Esclerose Múltipla)
dc.description.affiliationMédica Neuropediatra da UFU BCTRIMS
dc.description.affiliationFaculdade de Medicina de Botucatu UNESP, Botucatu SP
dc.description.affiliationBCTRIMS
dc.description.affiliationUFU CETEM BCTRIMS
dc.description.affiliationUFU
dc.description.affiliationDepartamento de Pediatria Faculdade de Medicina UFU
dc.description.affiliation, Rua Rodrigues da Cunha 790/1204-C, 38400-362 Uberlândia MG
dc.description.affiliationUnespFaculdade de Medicina de Botucatu UNESP, Botucatu SP
dc.identifier.doi10.1590/S0004-282X2007000300018
dc.identifier.scieloS0004-282X2007000300018
dc.identifier.wosWOS:000248225000018
dc.rights.accessRightsAcesso aberto
dc.identifier.scopus2-s2.0-34547614610
unesp.campusUniversidade Estadual Paulista (UNESP), Faculdade de Medicina, Botucatupt
dc.identifier.file2-s2.0-34547614610.pdf
dc.identifier.lattes4044986284615753
unesp.author.lattes4044986284615753
dc.relation.ispartofjcr1.015
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