Show simple item record

dc.contributor.authorGotardo, M. A. [UNESP]
dc.contributor.authorSequinel, R. [UNESP]
dc.contributor.authorPezza, Leonardo [UNESP]
dc.contributor.authorPezza, Helena Redigolo [UNESP]
dc.date.accessioned2014-05-27T11:23:40Z
dc.date.available2014-05-27T11:23:40Z
dc.date.issued2008-10-01
dc.identifierhttp://dx.doi.org/10.1590/S0100-46702008000400001
dc.identifier.citationEcletica Quimica, v. 33, n. 4, p. 7-12, 2008.
dc.identifier.issn0100-4670
dc.identifier.urihttp://hdl.handle.net/11449/70596
dc.description.abstractA simple analytical method for quantification of atenolol in pharmaceutical formulations by diffuse reflectance spectroscopy is described. The method is based on the reaction, on the filter paper surface, between the drug and p-chloranil producing a colored compound. The best reaction conditions were obtained with 20 μL of atenolol solution and 20 μL of p-chloranil. All reflectance measurements were carried out at 550 nm and the linear range was from 1.13×10-2 to 7.88×10-2 mol L-1 (r = 0.9992). The limit of detection was 2.80 × 10-3 mol L-1. The proposed method was successfully applied to analysis of different commercial brands of pharmaceutical formulations and the results obtained by the proposed method were in good agreement with those obtained using the British Pharmacopoeia method.en
dc.format.extent7-12
dc.language.isoeng
dc.relation.ispartofEclética Química
dc.sourceScopus
dc.subjectAtenolol
dc.subjectDiffuse reflectance spectroscopy
dc.subjectp-chloranil, pharmaceutical formulations
dc.titleDetermination of atenolol in pharmaceutical formulations by diffuse reflectance spectroscopyen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/eq/paboutj.htm
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.description.affiliationSao Paulo State University - UNESP Chemistry Institute of Araraquara, P.O. Box 355, 14801-970, Araraquara, SP
dc.description.affiliationUnespSao Paulo State University - UNESP Chemistry Institute of Araraquara, P.O. Box 355, 14801-970, Araraquara, SP
dc.identifier.doi10.1590/S0100-46702008000400001
dc.identifier.scieloS0100-46702008000400001
dc.rights.accessRightsAcesso aberto
dc.identifier.scopus2-s2.0-58649119855
unesp.campusUniversidade Estadual Paulista (UNESP), Instituto de Química, Araraquarapt
dc.identifier.file2-s2.0-58649119855.pdf
dc.identifier.lattes5978908591853524
dc.identifier.lattes3192125098361121
dc.identifier.orcid0000-0003-0197-7369
unesp.author.lattes5978908591853524
unesp.author.lattes3192125098361121
unesp.author.orcid0000-0003-0197-7369[3]
Localize o texto completo

Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record