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The effect of rifampicin and pyrazinamide on isoniazid pharmacokinetics in rats
(Biopharmaceutics & Drug Disposition, 2007-11-01) [Artigo]
Tuberculosis chemotherapy involves combination of the drugs isoniazid (INH), rifampicin (RMP) and pyrazinamide (PYR) for a 6-month period. The present work investigated the influence of RMP and PYR on the pharmacokinetic ...