Now showing items 1-10 of 374
Diapocynin versus apocynin as pretranscriptional inhibitors of NADPH oxidase and cytokine production by peripheral blood mononuclear cells
(Biochemical and Biophysical Research Communications, 2010-03-12) [Artigo]
Apocynin has been extensively used as an inhibitor of NADPH oxidase (NOX) in many experimental models using phagocytic and non-phagocytic cells. Currently, there is some controversy about the efficacy of apocynin in ...
Evaluation of the spouted bed dried leaf extract of Bauhinia forficata for the treatment of experimental diabetes in rats
(African Journal of Biotechnology, 2010-10-18) [Artigo]
Previously, we have demonstrated that treatment of experimental diabetes with a decoction of Bauhinia forficata leaves is beneficial. In this study, we prepared a two-fold concentrate of this extract and tested its effects ...
2-Bromo-1,4-naphthoquinone: a potentially improved substitute of menadione in Apatone therapy
(Brazilian Journal of Medical and Biological Research, 2012-08-01) [Artigo]
Apatone™, a combination of menadione (2-methyl-1,4-naphthoquinone, VK3) and ascorbic acid (vitamin C, VC) is a new strategy for cancer treatment. Part of its effect on tumor cells is related to the cellular pro-oxidative ...
It only takes one to do many jobs: Amphotericin B as antifungal and immunomodulatory drug
(Frontiers in Microbiology, 2012-12-01) [Artigo]
Amphotericin B acts through pore formation at the cell membrane after binding to ergosterol is an accepted dogma about the action mechanism of this antifungal, and this sentence is widely found in the literature. But after ...
Antitumor and immunomodulatory effects of the naphthoquinone 5-methoxy-3,4-dehydroxanthomegnin
(Revista Brasileira de Farmacognosia, 2011-12-01) [Artigo]
Large number of quinones has been associated with antitumor, antibacterial, antimalarial and antifungal activities. In this work we describe the effect of the naphthoquinone, 5-methoxy-3,4-dehydroxanthomegnin, on murine ...
Monitoring scaling and dental calculus removal with an optical fluorescence system
(Laser Physics, 2014-08-01) [Artigo]
Fluorescence results from a process that occurs under certain conditions in molecules known as fluorophores, fluorochromes or fluorescent dyes when they absorb light. The molecule is excited to a higher energy state and ...
Influence of a probiotic soy product on fecal microbiota and its association with cardiovascular risk factors in an animal model
(Lipids in Health and Disease, 2011-07-29) [Artigo]
Background: Previous work showed that daily ingestion of an aqueous soy extract fermented with Enterococcus faecium CRL 183 and Lactobacillus helveticus 416, supplemented or not with isoflavones, reduced the total cholesterol ...
A potential synbiotic product improves the lipid profile of diabetic rats
(Lipids in Health and Disease, 2012-09-11) [Artigo]
Background: Previous studies showed that intake of yacon or some lactic acid bacteria was able to inhibit the development of diabetes mellitus, by reducing glucose and associated symptoms, for example, the lipid ...
The Predominance of Alternatively Activated Macrophages Following Challenge with Cell Wall Peptide-Polysaccharide After Prior Infection with Sporothrix schenckii
(Mycopathologia, 2013-08-01) [Artigo]
Sporotrichosis is a subcutaneous mycosis that is caused by the dimorphic fungus Sporothrix schenckii. This disease generally occurs within the skin and subcutaneous tissues, causing lesions that can spread through adjacent ...
Expression of TH17 and HLA-G in cervical microenvironment in patients with cervical intraepithelial neoplasia
(Tissue Antigens, 2012-07-01) [Resumo]