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Papilomavirus Humano (HPV) - Um estudo de revisao
(Revista de Ciencias Farmaceuticas, 1999-12-01) [Resenha]
Human Papillomaviruses (HPVs) are epitheliotropic viruses, that induce benign and malignant lesions on several body sites. It's a small circular DNA virus, non-enveloped and 75 types have been identified. Frequently HPV ...
Interação das enterotoxinas estafilocócicas com o sistema imune do hospedeiro
(Revista de Ciencias Farmaceuticas, 2004-10-14) [Resenha]
Staphylococcal enterotoxins are among the most common etiologic agents that cause food poisoning and, possibly, nonmenstrual toxic shock syndrome. These enterotoxins are also called superantigens because they are potent T ...
Evolução no diagnóstico citológico do câncer de colo uterino - Novas tecnologias para o rastreamento citológico cervical
(Revista de Ciencias Farmaceuticas, 2003-12-01) [Resenha]
The cancer of the uterine cervix remains a serious public health problem in developing countries with low social-economic conditions. Papanicolaou smear has been used to screen women for cervical cancer since 1940, and it ...
SISTEMAS QUIMILUMINESCENTES COM PEROXIDASE (EC:1.11.1.7) E SUAS APLICACOES EM ANALISES CLINICAS
(Revista de Ciencias Farmaceuticas, 1995-01-01) [Resenha]
The enzyme horseradish peroxidase HRP (EC:1.11.1.7), has both acid and basic isoenzymes, catalyses a wide range of reactions (acting as an oxiredutase or an oxidase) and is thought capable of one- or two-electrons oxidations ...
A complexa fisiopatologia dos episódios vasooclusivos na anemia falciforme
(Revista de Ciencias Farmaceuticas, 2002-12-01) [Resenha]
Hemolytic anemia and vasoocclusion are the cardinal clinical features of sickle cell anemia. Vasoocclusion is a complex process involving not only the polymerization of deoxygenated sickle hemoglobin tetramers, but also ...
Doença arterial coronariana: Um novo paradigma na AIDS
(Revista de Ciencias Farmaceuticas, 2004-12-01) [Resenha]
The HIV-infected individuals have been identified as a peculiar group whose propensity to the development of abnormalities in lipids metabolism supports the hypothesis that AIDS itself can be considered as an independent ...
The multifaceted roles of metabolic enzymes in the Paracoccidioides species complex
(Frontiers In Microbiology, 2014-12-19) [Resenha]
Paracoccidioides species are dimorphic fungi and are the etiologic agents of paracoccidioidomycosis, which is a serious disease that involves multiple organs. The many tissues colonized by this fungus suggest a variety of ...
Protocatechuic Acid Alkyl Esters: Hydrophobicity As a Determinant Factor for Inhibition of NADPH Oxidase
(Current Medicinal Chemistry, 2012-10-01) [Resenha]
This study presents the increased efficiency of NADPH oxidase inhibition produced by esterification of protocatechuic acid (P0). Alkyl esters bearing chain lengths of 4 (P4), 7 (P7) and 10 (P10) carbons were synthesized ...
4 '-Aminochalcones As Novel Inhibitors of the Chlorinating Activity of Myeloperoxidase
(Current Medicinal Chemistry, 2012-11-01) [Resenha]
The excessive activation of neutrophils generates reactive oxygen species (ROS) and the secretion of primary granular enzymes, such as myeloperoxidase (MPO), which is implicated in numerous inflammatory diseases. The aim ...
Could histoplasma capsulatum be related to healthcare-associated infections?
(Biomed Research International, 2015-01-01) [Resenha]
Healthcare-associated infections (HAI) are described in diverse settings. The main etiologic agents of HAI are bacteria (85%) and fungi (13%). Some factors increase the risk for HAI, particularly the use of medical devices; ...