Now showing items 1-10 of 30
Influence of copper in the pattern of genes involved in the interaction of Paracoccidioides brasiliensis with the extracellular matrix component
(FASEB Journal, 2011-04-01) [Resumo]
Transcriptional profile of a bioethanol production contaminant Candida tropicalis
(AMB Express, 2018-12-01) [Artigo]
The fermentation process is widely used in the industry for bioethanol production. Even though it is widely used, microbial contamination is unpredictable and difficult to control. The problem of reduced productivity is ...
Can passage in Galleria mellonella activate virulence factors of Paracoccidioides brasiliensis as in the murine model?
(Medical Mycology, 2018-01-01) [Artigo]
Paracoccidioidomycosis (PCM) is a fungal disease restricted to Latin countries, and its etiologic agents derive from the Paracoccidioides genus. Attenuation or loss of virulence in Paracoccidioidesspp. following successive ...
Evaluation of the efficacy of antifungal drugs against Paracoccidioides brasiliensis and Paracoccidioides lutzii in a Galleria mellonella model
(International Journal of Antimicrobial Agents, 2016-09-01) [Artigo]
Paracoccidioides brasiliensis and P. lutzii belong to a group of thermodimorphic fungi and cause paracoccidioidomycosis (PCM), which is a human systemic mycosis endemic in South and Central America. Patients with this ...
Anti-Candida and anti-Cryptococcus evaluation of 15 non-alkaloidal compounds from Pterogyne nitens
(Asian Pacific Journal of Tropical Biomedicine, 2016-10-01) [Artigo]
Objective To evaluate anti-Candida and anti-Cryptococcus activities of 15 non-alkaloidal compounds from Pterogyne nitens Tulasne (Leguminosae), a South American medicinal plant. Methods Compounds were submitted to antifungal ...
Comparison of virulence between Paracoccidioides brasiliensis and Paracoccidioides lutzii using Galleria mellonella as a host model
(Virulence, 2015-01-01) [Artigo]
Paracoccidioidomycosis is a systemic mycosis, endemic in Latin America. The etiologic agents of this mycosis are composed of 2 species: Paracoccidioides brasiliensis and P. lutzii. Murine animal models are the gold standard ...
Advances and challenges in paracoccidioidomycosis serology caused by Paracoccidioides species complex: an update
(Diagnostic Microbiology And Infectious Disease, 2015) [Artigo]
Understanding the possible methodologies for the rapid and inexpensive identification of fungal infections is essential for disease diagnosis, but there are some limitations. To help with this problem, serological methods ...
Identification and characterisation of elongation factor Tu, a novel protein involved in Paracoccidioides brasiliensis-host interaction
(FEMS Yeast Research, 2016-11-01) [Artigo]
Paracoccidioides spp., which are temperature-dependent dimorphic fungi, are responsible for the most prevalent human systemic mycosis in Latin America, the paracoccidioidomycosis. The aim of this study was to characterise ...
Functional analysis of Paracoccidioides brasiliensis 14-3-3 adhesin expressed in Saccharomyces cerevisiae Microbe-host interactions and microbial pathogenicity
(BMC Microbiology, 2015-11-04) [Artigo]
Background: 14-3-3 proteins comprise a family of eukaryotic multifunctional proteins involved in several cellular processes. The Pb14-3-3 of Paracoccidioides brasiliensis seems to play an important role in the Paracoccid ...
Searching new antifungals: The use of in vitro and in vivo methods for evaluation of natural compounds
(Journal of Microbiological Methods, 2016-04-01) [Resenha]
In the last decades, the increased number of immunocompromised patients has led to the emergence of many forms of fungal infections. Furthermore, there are a restricted arsenal of antifungals available and an increase in ...