Now showing items 1-10 of 52
Avaliação do estresse oxidativo no sangue de consumidores habituais de suco de laranja
(Revista de Ciências Farmacêuticas Básica e Aplicada, 2011-11-14) [Artigo]
Two biomarkers of oxidative stress were evaluated in healthy volunteers treated with daily doses of orange juice that is well known source of vitamin C and citric flavanones, which have been associated with antioxidant, ...
Cytokines production in mice bearing breast tumor treated with pulchellin
(Cytokine, 2011-10-01) [Resumo]
Immune Response Against Sporothrix schenckii in TLR-4-Deficient Mice
(Mycopathologia, 2012-07-01) [Artigo]
For many fungal diseases, macrophages are the major cell population implicated in host protection, primarily by their ability to eliminate the invading fungal pathogen through phagocytosis. In sporotrichosis, this remains ...
Antitumor and immunomodulatory effects of the naphthoquinone 5-methoxy-3,4-dehydroxanthomegnin
(Revista Brasileira de Farmacognosia, 2011-12-01) [Artigo]
Large number of quinones has been associated with antitumor, antibacterial, antimalarial and antifungal activities. In this work we describe the effect of the naphthoquinone, 5-methoxy-3,4-dehydroxanthomegnin, on murine ...
Inhibition of Nitric Oxide and Tumour Necrosis Factor-alpha Production in Peritoneal Macrophages by Aspergillus nidulans Melanin
(Biological & Pharmaceutical Bulletin, 2013-12-01) [Artigo]
The naturally occurring pigment, melanin is found in organisms of all phylogenetic kingdoms, including fungi, and exhibits a wide range of biological activities. Our objective was to investigate the effects of melanin ...
Anti-inflammatory activity of Alchornea triplinervia ethyl acetate fraction: Inhibition of H2O2, NO and TNF-alpha
(Pharmaceutical Biology, 2010-12-01) [Artigo]
Context: Alchornea triplinervia (Spreng.) Mull. Arg. (Euphorbiaceae) is a tree widespread in many Brazilian states. This plant naturally occurs in different ecosystems including tropical Atlantic forest, Amazon rain forest, ...
Comparative efficacy and toxicity of two vaccine candidates against Sporothrix schenckii using either Montanide™ Pet Gel A or aluminum hydroxide adjuvants in mice
(Vaccine, 2017-08-03) [Artigo]
Sporotrichosis is an important zoonosis in Brazil and the most frequent subcutaneous mycosis in Latin America, caused by different Sporothrix species. Currently, there is no effective vaccine available to prevent this ...
Biocompatible Microemulsion Modifies the Tissue Distribution of Doxorubicin
(Journal Of Pharmaceutical Sciences, 2014-10-01) [Artigo]
The incorporation of doxorubicin (DOX) in a microemulsion (DOX-ME) has shown beneficial consequences by reducing the cardiotoxic effects of DOX. The aim of this study was to determine the distribution of DOX-ME in Ehrlich ...
Systemic immunotoxicity reactions induced by adjuvanted vaccines
(International Immunopharmacology, 2014-05-01) [Artigo]
Vaccine safety is a topic of concern for the treated individual, the family, the health care personnel, and the others involved in vaccination programs as recipients or providers. Adjuvants are necessary components to ...
Effector proteins from Yersinia pseudotuberculosis influence cytokines expression in T lymphocytes subpopulations
(Cytokine, 2011-10-01) [Resumo]