Now showing items 11-20 of 49
Induction and secretion of elastinolytic and proteolytic activity in cultures of Paracoccidioides brasiliensis
(Revista de Ciências Farmacêuticas Básica e Aplicada, 2008-10-28) [Artigo]
P. brasiliensis parasitizes various human tissues and proteinases exported by this fungus may allow it to metabolize and invade host tissues. The influence of the culture medium on the production of proteinases by P. ...
Comparative study of disk diffusion and microdilution methods for evaluation of antifungal activity of natural compounds against medical yeasts Candida spp and Cryptococcus sp
(Revista de Ciências Farmacêuticas Básica e Aplicada, 2007-12-01) [Artigo]
Antifungal activity of natural products has been tested by adapting methods designed for synthetic drugs. In this study, two methods for the determination of antifungal activity of natural products, agar diffusion and broth ...
Pathogenesis II: Fungal responses to host responses: interaction of host cells with fungi
(Medical Mycology, 2000-01-01) [Artigo]
Most of our knowledge concerning the virulence determinants of pathogenic fungi comes from the infected host, mainly from animal models and more recently from in vitro studies with cell cultures. The fungi usually present ...
cDNA representational difference analysis used in the identification of genes expressed by Trichophyton rubrum during contact with keratin
(Microbes And Infection / Institut Pasteur, 2007) [Artigo]
Dermatophytes are adapted to infect skin, hair and nails by their ability to utilize keratin as a nutrient source. Trichophyton rubrum is an anthropophilic fungus, causing up to 90% of chronic cases of dermatophytosis. The ...
Epithelial cells treated with genistein inhibit adhesion and endocytosis of Paracoccidioides brasiliensis
(Antonie Van Leeuwenhoek International Journal of General and Molecular Microbiology, 2007-07-01) [Artigo]
Paracoccidioidomycosis is caused by Paracoccidioides brasiliensis, which although not formally considered an intracellular pathogen, can be internalized by epithelial cells in vitro and in vivo. The mechanisms used by P. ...
The role of interleukin-10 in the differential expression of interleukin-12p70 and its beta 2 receptor on patients with active or treated paracoccidioidomycosis and healthy infected subjects
(Clinical Immunology, 2005-01-01) [Artigo]
Paracoccidioidomycosis patients present an antigen-specific Th1 immunosuppression. To better understand this phenomenon, we evaluated the interleukin (IL)-12 pathway by measuring IL-12p70 production and CD3(+) T cell ...
IL-12 and neutralization of endogenous IL-10 revert the in vitro antigen-specific cellular immunosuppression of paracoccidioidomycosis patients
(Cytokine, 2002-07-25) [Artigo]
Treatment of patients with paracoccidioidomycosis is still a challenge. Patients present defective lymphoproliferation and IFN-γ responses to the main Paracoccidioides brasiliensis antigen (gp43), which correlates with ...
Oral carriage of Candida spp., denture cleanliness, ABO blood groups. and denture stomatitis in Brazilian patients.
(Journal of Dental Research, 2003-06-01) [Resumo]
Correlation between denture stomatitis, candida spp., blood group, denture cleanliness. A preliminary study.
(Journal of Dental Research, 2003-12-01) [Resumo]
Invasion of epithelial mammalian cells by Paracoccidioides brasiliensis leads to cytoskeletal rearrangement and apoptosis of the host cell
(Microbes and Infection, 2004-08-01) [Artigo]
Paracoccidioides brasiliensis (Pb) yeast cells can enter mammalian cells and probably manipulate the host cell environment to favor their own growth and survival. We studied the uptake of strain Pb 18 into A549 lung and ...