Now showing items 1-10 of 35
Estudo fitoquímico de goiaba (Psidium guajava L.) com potencial antioxidante para o desenvolvimento de formulação fitocosmética
(Revista Brasileira de Farmacognosia, 2008-09-01) [Artigo]
Considerando-se a qualidade dos fitoterápicos, é importante salientar que a preocupação com esta questão inclui rigoroso acompanhamento das diferentes etapas do desenvolvimento e produção destes produtos, desde a coleta ...
Diagnosis of Smith-Lemli-Opitz syndrome by ultraviolet spectrophotometry
(Brazilian Journal of Medical and Biological Research, 2003-10-01) [Artigo]
Smith-Lemli-Opitz syndrome (SLOS) is an autosomal recessive disorder due to an inborn error of cholesterol metabolism, characterized by congenital malformations, dysmorphism of multiple organs, mental retardation and delayed ...
Antioxidant activity of Agaricus blazei
(Fitoterapia, 2007-04-01) [Artigo]
The ethanolic extract of Agaricus blazei and ethyl acetate and hydroalcoholic fractions were evaluated for their antioxidant activity. (C) 2007 Elsevier B.V. All rights reserved.
Dissociation between the circulating renin-angiotensin system and angiotensin II receptors in central losartan-induced hypertension
(Brazilian Journal of Medical and Biological Research, 2002-09-01) [Artigo]
Losartan, an AT1 angiotensin II (ANG II) receptor non-peptide antagonist, induces an increase in mean arterial pressure (MAP) when injected intracerebroventricularly (icv) into rats. The present study investigated possible ...
Tratamento crônico com extrato alcoólico de Pterogyne nitens não melhora parâmetros clássicos do diabetes experimental
(Revista Brasileira de Farmacognosia, 2009-06-01) [Artigo]
Tem sido atribuído ao flavonóide kaempferitrina e ao alcalóide galegina efeito hipoglicêmico. Folha de Pterogyne nitens, por conter tais compostos, poderia ser antidiabética. Assim, avaliamos o efeito do tratamento com ...
Indole ring oxidation by activated leukocytes prevents the production of hypochlorous acid
(Brazilian Journal of Medical and Biological Research, 2005-11-01) [Artigo]
Hypochlorous acid (HOCl) released by activated leukocytes has been implicated in the tissue damage that characterizes chronic inflammatory diseases. In this investigation, 14 indole derivatives, including metabolites such ...
Profile of Maytenus aquifolium action over free radicals and reactive oxygen species
(Revista Brasileira de Ciencias Farmaceuticas/Brazilian Journal of Pharmaceutical Sciences, 2007-07-01) [Artigo]
Reactive oxygen species (ROS) and free radical species have been implicated in initiating, accompanying or causing many diseases in living organisms; there is thus, a continual need for antioxidants molecules to inactivate ...
Does cotinine act upon reactive oxygen species and peroxidases?
(Eclética Química, 2007-06-19) [Artigo]
Nicotine, an oxidizing agent, is certainly one of the most widely used alkaloids in the world. It is, together with its main metabolite, cotinine, responsible for tobacco-dependence. The use of tobacco is closely associated ...
Antioxidant activity of Maytenus ilicifolia root bark
(Fitoterapia, 2006-04-01) [Artigo]
Maytenus ilicifolia is an important plant with potential on cancer treatment and has been largely used in Brazil and other countries. We have evaluated the crude ethanolic extract of M. ilicifolia as a potential antioxidant ...
The reactivity of oytho-methoxy-substituted catechol radicals with sulfhydryl groups: Contribution for the comprehension of the mechanism of inhibition of NADPH oxidase by apocynin
(Biochemical Pharmacology, 2007-08-01) [Artigo]
Redox processes are involved in the mechanism of action of NADPH oxidase inhibitors such as diphenyleneiodonium and apocynin. Here, we studied the structure-activity relationship for apocynin and analogous ortho-methoxy- ...