Now showing items 1-10 of 35
Influence of copper in the pattern of genes involved in the interaction of Paracoccidioides brasiliensis with the extracellular matrix component
(FASEB Journal, 2011-04-01) [Resumo]
Synthesis and characterization of an antibacterial and non-toxic dimeric peptide derived from the C-terminal region of Bothropstoxin-I
(Toxicon : Official Journal Of The International Society On Toxinology, 2015) [Artigo]
Infectious diseases are among the leading global causes of death, increasing the search for novel antibacterial agents. Among these, biologically active peptides are an excellent research tool. Using solid-phase peptide ...
Antifungal Activity of Decyl Gallate against Several Species of Pathogenic Fungi
(Evidence-based Complementary And Alternative Medicine, 2014-01-01) [Artigo]
This work aims to demonstrate that the gallic acid structure modification to the decyl gallate (G14) compound contributed to increase the antifungal activity against several species of pathogenic fungi, mainly, Candida ...
A flow cytometry method for testing the susceptibility of Cryptococcus spp. to amphotericin B
(Revista Iberoamericana De Micología, 2015) [Artigo]
Human fungal infections have increased at an alarming rate in recent years, particularly in immunocompromised individuals. Cryptococcosis is the second most prevalent systemic fungal infection worldwide, and the most ...
Anti-apoptotic effects of decyl gallate on the induction of apoptosis in A549 pneumocytes by Paracoccidioides brasiliensis gp43
(Medical Mycology, 2017-11-01) [Artigo]
Apoptosis is considered an escapemechanism from the host immune system for the fungus Paracoccidioides spp, and it serves as a vehicle for entry into macrophages without stimulating microbicidal activities. Recently, gp43 ...
Advances and challenges in paracoccidioidomycosis serology caused by Paracoccidioides species complex: an update
(Diagnostic Microbiology And Infectious Disease, 2015) [Artigo]
Understanding the possible methodologies for the rapid and inexpensive identification of fungal infections is essential for disease diagnosis, but there are some limitations. To help with this problem, serological methods ...
Synergistic effect of pedalitin and amphotericin B against Cryptococcus neoformans by in vitro and in vivo evaluation
(International Journal of Antimicrobial Agents, 2016-11-01) [Artigo]
Cryptococcosis is an opportunistic fungal infection responsible for high morbidity and mortality in immunocompromised patients. Combination of antifungal substances is a promising way to increase the percentage of successful ...
Preliminary evaluation of circulating microRNAs as potential biomarkers in paracoccidioidomycosis
(Biomedical Reports, 2017-03-01) [Artigo]
MicroRNAs (miRNAs) are small RNAs (length, 19-24 nucleotides) that regulate gene expression by either mRNA degradation or translational inhibition of proteins. Circulating miRNAs, which are extremely stable and protected ...
Identification and characterisation of elongation factor Tu, a novel protein involved in Paracoccidioides brasiliensis-host interaction
(FEMS Yeast Research, 2016-11-01) [Artigo]
Paracoccidioides spp., which are temperature-dependent dimorphic fungi, are responsible for the most prevalent human systemic mycosis in Latin America, the paracoccidioidomycosis. The aim of this study was to characterise ...
Comparison of virulence between Paracoccidioides brasiliensis and Paracoccidioides lutzii using Galleria mellonella as a host model
(Virulence, 2015-01-01) [Artigo]
Paracoccidioidomycosis is a systemic mycosis, endemic in Latin America. The etiologic agents of this mycosis are composed of 2 species: Paracoccidioides brasiliensis and P. lutzii. Murine animal models are the gold standard ...