Now showing items 1-10 of 55
Effect of different pre-irradiation times on curcumin-mediated photodynamic therapy against planktonic cultures and biofilms of Candida spp
(Archives of Oral Biology, 2013-02-01) [Artigo]
Objectives: The aim of this study was to evaluate the effects of pre-irradiation time (PIT) on curcumin (Cur)-mediated photodynamic therapy (PDT) against planktonic and biofilm cultures of reference strains of Candida ...
Modulation of HJURP (Holliday Junction-Recognizing Protein) Levels Is Correlated with Glioblastoma Cells Survival
(PLOS ONE, 2013-04-25) [Artigo]
Background: Diffuse astrocytomas are the most common type of primary brain cancer in adults. They present a wide variation in differentiation and aggressiveness, being classified into three grades: low-grade diffuse ...
Microplate alamarblue assay for paracoccidioides susceptibility testing
(Journal of Clinical Microbiology, 2013-04-01) [Artigo]
CLSI method M27-A3 is not available for use with dimorphic fungi, such as those of the Paracoccidioides genus. In this study, we developed a microdilution method and added the alamarBlue reagent to test the responses of ...
Brief Report: The lincRNA Hotair Is Required for Epithelial-to-Mesenchymal Transition and Stemness Maintenance of Cancer Cell Lines
(Stem Cells, 2013-12-01) [Artigo]
Hotair is a member of the recently described class of noncoding RNAs called lincRNA (large intergenic noncoding RNA). Various studies suggest that Hotair acts regulating epigenetic states by recruiting chromatin-modifying ...
Assessment of the chemopreventive effect of casearin B, a clerodane diterpene extracted from Casearia sylvestris (Salicaceae)
(Food and Chemical Toxicology, 2013-03-01) [Artigo]
Studies have shown that Casearia sylvestris compounds protect DNA from damage both in vitro and in vivo. Complementarily, the aim of the present study was to assess the chemopreventive effect of casearin B (CASB) against ...
Intermolecular interactions of the malate synthase of Paracoccidioides spp
(BMC Microbiology, 2013-05-16) [Artigo]
Background: The fungus Paracoccidioides spp is the agent of paracoccidioidomycosis (PCM), a pulmonary mycosis acquired by the inhalation of fungal propagules. Paracoccidioides malate synthase (PbMLS) is important in the ...
Paracoccidoides brasiliensis 30 kDa Adhesin: Identification as a 14-3-3 Protein, Cloning and Subcellular Localization in Infection Models
(PLOS ONE, 2013-04-30) [Artigo]
Paracoccidoides brasiliensis adhesion to lung epithelial cells is considered an essential event for the establishment of infection and different proteins participate in this process. One of these proteins is a 30 kDa ...
Frequency and genetic diversity of the MAT1 locus of Histoplasma capsulatum isolates in Mexico and Brazil
(Eukaryotic Cell, 2013-07-01) [Artigo]
The MAT1-1 and MAT1-2 idiomorphs associated with the MAT1 locus of Histoplasma capsulatum were identified by PCR. A total of 28 fungal isolates, 6 isolates from human clinical samples and 22 isolates from environmental ...
Oxidative stress in diabetes and periodontitis
(North American Journal of Medical Sciences, 2013-01-01) [Artigo]
Inhibition of Nitric Oxide and Tumour Necrosis Factor-alpha Production in Peritoneal Macrophages by Aspergillus nidulans Melanin
(Biological & Pharmaceutical Bulletin, 2013-12-01) [Artigo]
The naturally occurring pigment, melanin is found in organisms of all phylogenetic kingdoms, including fungi, and exhibits a wide range of biological activities. Our objective was to investigate the effects of melanin ...