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Comparative efficacy and toxicity of two vaccine candidates against Sporothrix schenckii using either Montanide™ Pet Gel A or aluminum hydroxide adjuvants in mice
(Vaccine, 2017-08-03) [Artigo]
Sporotrichosis is an important zoonosis in Brazil and the most frequent subcutaneous mycosis in Latin America, caused by different Sporothrix species. Currently, there is no effective vaccine available to prevent this ...
Antifungal properties of high efficient W/WO3 electrodes acting under UV-Vis and visible light and chloride medium
(Journal of the Brazilian Chemical Society, 2017-11-01) [Artigo]
The present work investigates the use of W/WO3 electrodes prepared by electrochemical anodization applied in the photoelectrocatalytic disinfection of Candida parapsilosis using ultraviolet-visible (UV-Vis) and visible ...
Octyl gallate, a food additive with potential beneficial properties to treat: Helicobacter pylori infection
(Food and Function, 2017-07-01) [Artigo]
Helicobacter pylori infection is marked by intense production of reactive oxygen species (ROS) through the activation of neutrophils that are constantly attracted to the infected gastric mucosa. Here, gallic acid and its ...
Influence of cimetidine and experimental diabetes mellitus on gabapentin pharmacokinetics in rats
(Toxicology Letters, 2017-10-20) [Resumo]
Anti-apoptotic effects of decyl gallate on the induction of apoptosis in A549 pneumocytes by Paracoccidioides brasiliensis gp43
(Medical Mycology, 2017-11-01) [Artigo]
Apoptosis is considered an escapemechanism from the host immune system for the fungus Paracoccidioides spp, and it serves as a vehicle for entry into macrophages without stimulating microbicidal activities. Recently, gp43 ...
Highlights in endocytosis of nanostructured systems
(Current Medicinal Chemistry, 2017-06-01) [Resenha]
The focus of this review is the cellular internalisation mechanism of nanostructured systems (NSs) and their endosomal escape for targeted drug delivery. Endocytosis is a cellular process of internalisation of different ...
Chemical composition and in vitro chemoprevention assessment of Eugenia jambolana Lam. (Myrtaceae) fruits and leaves
(Journal of Functional Foods, 2017-09-01) [Artigo]
Eugenia jambolana has been used as an antioxidant, anti-inflammatory and antidiabetic. This study performed a chemical and chemopreventive screening of extracts and fractions from leaves and fruits from Eugenia jambolana. ...
Optimization of Antimicrobial Photodynamic Therapy in Biofilms by Inhibiting Efflux Pump
(Photomedicine and Laser Surgery, 2017-07-01) [Artigo]
Background: One of the main mechanisms of microbial resistance is given by efflux pumps, which reduce the effectiveness of antimicrobials by decreasing their intracellular concentration. Objective and methods: Considering ...
Avaliação da pentoxifilina, inibidor não-seletivo de fosfodiesterases, sobre biomarcadores do estresse oxidativo e glicativo em camundongos submetidos à modelo de obesidade e intolerância à glicose
(Revista de Ciencias Farmaceuticas Basica e Aplicada, 2017-01-01) [Artigo]
Orange juice as dietary source of antioxidants for patients with hepatitis C under antiviral therapy
(Food and Nutrition Research, 2017-03-22) [Artigo]
Background: HCV causes alterations in liver metabolism, resulting in biochemical and nutritional disorders. Supplementation with antioxidants has been suggested to minimize the diseases effects. Objective: This study ...