Now showing items 1-10 of 14
Microplate alamarblue assay for paracoccidioides susceptibility testing
(Journal of Clinical Microbiology, 2013-04-01) [Artigo]
CLSI method M27-A3 is not available for use with dimorphic fungi, such as those of the Paracoccidioides genus. In this study, we developed a microdilution method and added the alamarBlue reagent to test the responses of ...
In vitro Paracoccidioides brasiliensis biofilm and gene expression of adhesins and hydrolytic enzymes
(Virulence, 2015-08-18) [Artigo]
Paracoccidioides species are dimorphic fungi that initially infect the lungs but can also spread throughout the body. The spreading infection is most likely due to the formation of a biofilm that makes it difficult for the ...
Anti-apoptotic effects of decyl gallate on the induction of apoptosis in A549 pneumocytes by Paracoccidioides brasiliensis gp43
(Medical Mycology, 2017-11-01) [Artigo]
Apoptosis is considered an escapemechanism from the host immune system for the fungus Paracoccidioides spp, and it serves as a vehicle for entry into macrophages without stimulating microbicidal activities. Recently, gp43 ...
Identification and characterisation of elongation factor Tu, a novel protein involved in Paracoccidioides brasiliensis-host interaction
(FEMS Yeast Research, 2016-11-01) [Artigo]
Paracoccidioides spp., which are temperature-dependent dimorphic fungi, are responsible for the most prevalent human systemic mycosis in Latin America, the paracoccidioidomycosis. The aim of this study was to characterise ...
Functional analysis of Paracoccidioides brasiliensis 14-3-3 adhesin expressed in Saccharomyces cerevisiae Microbe-host interactions and microbial pathogenicity
(BMC Microbiology, 2015-11-04) [Artigo]
Background: 14-3-3 proteins comprise a family of eukaryotic multifunctional proteins involved in several cellular processes. The Pb14-3-3 of Paracoccidioides brasiliensis seems to play an important role in the Paracoccid ...
Corrigendum: importance of adhesins in virulence of paracoccidioides spp
(Frontiers In Microbiology, 2015) [Artigo]
Evaluation of Caenorhabditis elegans as a host model for Paracoccidioides brasiliensis and Paracoccidioides lutzii
(Pathogens and Disease, 2018-02-01) [Artigo]
Paracoccidioidomycosis is a systemic fungal infection affecting mainly Latin American countries that is caused by Paracoccidioides brasiliensis and Paracoccidioides lutzii. During the study of fungal pathogenesis, in vivo ...
Alkyl Protocatechuate-Loaded Nanostructured Lipid Systems as a Treatment Strategy for Paracoccidioides brasiliensis and Paracoccidioides lutzii In Vitro
(Frontiers In Microbiology, 2017-06-12) [Artigo]
Dodecyl protocatechuate (dodecyl) is a derivative of protocatechuic acid (3,4dihydroxybenzoic acid) that possesses anti-oxidant and antifungal properties. Nanostructured lipid systems (NLS) can potentiate the action of ...
Surface-expressed enolase contributes to the adhesion of Paracoccidioides brasiliensis to host cells
(FEMS Yeast Research, 2012-08-01) [Artigo]
Paracoccidioidomycosis is a systemic mycosis caused by the dimorphic fungus Paracoccidioides brasiliensis. Understanding the interactions between P.similar to brasiliensis and the host tissue depends on the study of the ...
Comparative transcriptome analysis of Paracoccidioides brasiliensis during in vitro adhesion to type I collagen and fibronectin: identification of potential adhesins
(Research in Microbiology, 2012-04-01) [Artigo]
Paracoccidioidomycosis is caused by the dimorphic fungus Paracoccidioides brasiliensis. The extracellular matrix (ECM) plays an important role in regulation of cell adhesion, differentiation, migration and proliferation ...