Now showing items 1-8 of 8
Antioxidant activity of Agaricus blazei
(Fitoterapia, 2007-04-01) [Artigo]
The ethanolic extract of Agaricus blazei and ethyl acetate and hydroalcoholic fractions were evaluated for their antioxidant activity. (C) 2007 Elsevier B.V. All rights reserved.
Profile of Maytenus aquifolium action over free radicals and reactive oxygen species
(Revista Brasileira de Ciencias Farmaceuticas/Brazilian Journal of Pharmaceutical Sciences, 2007-07-01) [Artigo]
Reactive oxygen species (ROS) and free radical species have been implicated in initiating, accompanying or causing many diseases in living organisms; there is thus, a continual need for antioxidants molecules to inactivate ...
Does cotinine act upon reactive oxygen species and peroxidases?
(Eclética Química, 2007-06-19) [Artigo]
Nicotine, an oxidizing agent, is certainly one of the most widely used alkaloids in the world. It is, together with its main metabolite, cotinine, responsible for tobacco-dependence. The use of tobacco is closely associated ...
The reactivity of oytho-methoxy-substituted catechol radicals with sulfhydryl groups: Contribution for the comprehension of the mechanism of inhibition of NADPH oxidase by apocynin
(Biochemical Pharmacology, 2007-08-01) [Artigo]
Redox processes are involved in the mechanism of action of NADPH oxidase inhibitors such as diphenyleneiodonium and apocynin. Here, we studied the structure-activity relationship for apocynin and analogous ortho-methoxy- ...
The effect of pyrazinamide and rifampicin on isoniazid metabolism in rats
(Biopharmaceutics & Drug Disposition, 2007-09-01) [Artigo]
Hepatotoxicity is the main concern during tuberculosis chemotherapy with the first-line drugs isoniazid (INH), rifampicin (RMP) and pyrazinamide (PYR). Since these hepatotoxic events have been associated with INH metabolites, ...
The effect of rifampicin and pyrazinamide on isoniazid pharmacokinetics in rats
(Biopharmaceutics & Drug Disposition, 2007-11-01) [Artigo]
Tuberculosis chemotherapy involves combination of the drugs isoniazid (INH), rifampicin (RMP) and pyrazinamide (PYR) for a 6-month period. The present work investigated the influence of RMP and PYR on the pharmacokinetic ...
Chemiluminescent determination of leukocyte alkaline phosphatase: An advantageous alternative to the cytochemical assay
(Journal of Clinical Laboratory Analysis, 2007-01-01) [Artigo]
The determination of leukocyte alkaline phosphatasd (LAP) is used as an aid to diagnose many diseases in the laboratory. For example, it can be used to distinguish chronic myeloid leukemia (CML) from other myeloproliferative ...
Candida albicans inactivation and cell membrane integrity damage by microwave irradiation
(Mycoses, 2007-03-01) [Artigo]
In indicating the microwave irradiation for disinfecting dentures it is necessary to see how this procedure influences Candida albicans integrity and viability. The aim of this study was to evaluate the ability of microwaves ...