Now showing items 1-6 of 6
Selective photoinactivation of Histoplasma capsulatum by water-soluble derivatives chalcones
(Photodiagnosis And Photodynamic Therapy, 2017-06-01) [Artigo]
Histoplasmosis is a respiratory and systemic disease caused by the dimorphic fungus Histoplasma capsulatum. The clinical features may vary from asymptomatic infections to disseminated severe form depending of patient ...
Synthesis, antioxidant and anti-inflammatory properties of an apocynin-derived dihydrocoumarin
(Medicinal Chemistry, 2017-01-01) [Artigo]
Background: Coumarin derivatives as dihydrocoumarins have been reported to have multiple biological activities, such as antioxidant and anti-inflammatory properties. Apocynin (APO), which is a substituted-methoxy-catechol, ...
Alkyl Protocatechuate-Loaded Nanostructured Lipid Systems as a Treatment Strategy for Paracoccidioides brasiliensis and Paracoccidioides lutzii In Vitro
(Frontiers In Microbiology, 2017-06-12) [Artigo]
Dodecyl protocatechuate (dodecyl) is a derivative of protocatechuic acid (3,4dihydroxybenzoic acid) that possesses anti-oxidant and antifungal properties. Nanostructured lipid systems (NLS) can potentiate the action of ...
Highlights in nanocarriers for the treatment against cervical cancer
(Materials Science and Engineering C, 2017-11-01) [Resenha]
Cervical cancer is the second most common malignant tumor in women worldwide and has a high mortality rate, especially when it is associated with human papillomavirus (HPV). In US, an estimated 12,820 cases of invasive ...
Efficacy of a binuclear cyclopalladated compound therapy for cutaneous leishmaniasis in the murine model of infection with Leishmania amazonensis and its inhibitory effect on topoisomerase 1B
(Antimicrobial Agents and Chemotherapy, 2017-08-01) [Artigo]
Leishmaniasis is a disease found throughout the (sub)tropical parts of the world caused by protozoan parasites of the Leishmania genus. Despite the numerous problems associated with existing treatments, pharmaceutical ...
Fungal biofilms and polymicrobial diseases
(Journal of Fungi, 2017-06-01) [Resenha]
Biofilm formation is an important virulence factor for pathogenic fungi. Both yeasts and filamentous fungi can adhere to biotic and abiotic surfaces, developing into highly organized communities that are resistant to ...