Now showing items 1-6 of 6
Anti-Immune Strategies of Pathogenic Fungi
(Frontiers In Cellular And Infection Microbiology, 2016-11-15) [Resenha]
Pathogenic fungi have developed many strategies to evade the host immune system. Multiple escape mechanisms appear to function together to inhibit attack by the various stages of both the adaptive and the innate immune ...
Highlights in endocytosis of nanostructured systems
(Current Medicinal Chemistry, 2017-06-01) [Resenha]
The focus of this review is the cellular internalisation mechanism of nanostructured systems (NSs) and their endosomal escape for targeted drug delivery. Endocytosis is a cellular process of internalisation of different ...
Paracoccidioides-host interaction: An overview on recent advances in the paracoccidioidomycosis
(Frontiers in Microbiology, 2015-01-01) [Resenha]
Paracoccidioides brasiliensis and P. lutzii are etiologic agents of paracoccidioidomycosis (PCM), an important endemic mycosis in Latin America. During its evolution, these fungi have developed characteristics and mechanisms ...
Antifungal therapy: New advances in the understanding and treatment of mycosis
(Frontiers in Microbiology, 2017-01-23) [Resenha]
The high rates of morbidity and mortality caused by fungal infections are associated with the current limited antifungal arsenal and the high toxicity of the compounds. Additionally, identifying novel drug targets is ...
Highlights in nanocarriers for the treatment against cervical cancer
(Materials Science and Engineering C, 2017-11-01) [Resenha]
Cervical cancer is the second most common malignant tumor in women worldwide and has a high mortality rate, especially when it is associated with human papillomavirus (HPV). In US, an estimated 12,820 cases of invasive ...
The multifaceted roles of metabolic enzymes in the Paracoccidioides species complex
(Frontiers In Microbiology, 2014-12-19) [Resenha]
Paracoccidioides species are dimorphic fungi and are the etiologic agents of paracoccidioidomycosis, which is a serious disease that involves multiple organs. The many tissues colonized by this fungus suggest a variety of ...