Now showing items 1-6 of 6
Searching new antifungals: The use of in vitro and in vivo methods for evaluation of natural compounds
(Journal of Microbiological Methods, 2016-04-01) [Resenha]
In the last decades, the increased number of immunocompromised patients has led to the emergence of many forms of fungal infections. Furthermore, there are a restricted arsenal of antifungals available and an increase in ...
Fungal diseases: could nanostructured drug delivery systems be a novel paradigm for therapy?
(International Journal Of Nanomedicine, 2016-01-01) [Resenha]
Invasive mycoses are a major problem for immunocompromised individuals and patients in intensive care units. Morbidity and mortality rates of these infections are high because of late diagnosis and delayed treatment. ...
Could histoplasma capsulatum be related to healthcare-associated infections?
(Biomed Research International, 2015-01-01) [Resenha]
Healthcare-associated infections (HAI) are described in diverse settings. The main etiologic agents of HAI are bacteria (85%) and fungi (13%). Some factors increase the risk for HAI, particularly the use of medical devices; ...
Applications of invertebrate animal models to dimorphic fungal infections
(Journal of Fungi, 2018-01-01) [Resenha]
Dimorphic fungi can be found in the yeast form during infection and as hyphae in the environment and are responsible for a large number of infections worldwide. Invertebrate animals have been shown to be convenient models ...
Transcriptomic crosstalk between fungal invasive pathogens and their host cells: Opportunities and challenges for next-generation sequencing methods
(Journal of Fungi, 2016-03-01) [Resenha]
Fungal invasive infections are an increasing health problem. The intrinsic complexity of pathogenic fungi and the unmet clinical need for new and more effective treatments requires a detailed knowledge of the infection ...
Fungal biofilms and polymicrobial diseases
(Journal of Fungi, 2017-06-01) [Resenha]
Biofilm formation is an important virulence factor for pathogenic fungi. Both yeasts and filamentous fungi can adhere to biotic and abiotic surfaces, developing into highly organized communities that are resistant to ...